Altered Histone Acetylation at Glutamate Receptor 2 and Brain-Derived Neurotrophic Factor Genes Is an Early Event Triggered by Status Epilepticus

This work was supported by grants from the National Institutes of Health–National Institute of Neurological Disorders and Stroke (R.D.) and the Culpepper Foundation (J.J.D.). We thank Drs. Gianmaria Maccaferri and David Mott for slice preparation.

Correspondence should be addressed to Ray Dingledine, Department of Pharmacology, Emory University School of Medicine, 1510 Clifton Road, Atlanta, GA 30322. E-mail: rdingledine{at}pharm.emory.edu.

Y. Huang's present address: Department of Neuroscience, The Johns Hopkins University School of Medicine, Baltimore, MD 21205.

J. J. Doherty's present address: AstraZeneca Pharmaceuticals, Wilmington, DE 19803.