Long-Term Potentiation in Hippocampus Involves Sequential Activation of Soluble Guanylate Cyclase, cGMP-Dependent Protein Kinase, and cGMP-Degrading Phosphodiesterase

Pilar Monfort; Marı́a-Dolores Muñoz; Elena Kosenko; Vicente Felipo

doi:10.1523/JNEUROSCI.22-23-10116.2002

Article Information

DOI

https://doi.org/10.1523/JNEUROSCI.22-23-10116.2002

PubMed

12451112

Published By

Society for Neuroscience

History

Received May 2, 2002
Revision received September 10, 2002
Accepted September 10, 2002
First published December 1, 2002.

Version of record published December 1, 2002.

Author Information

Pilar Monfort,
Marı́a-Dolores Muñoz,
Elena Kosenko, and
Vicente Felipo

¹Instituto de Investigaciones Citológicas, Fundación Valenciana de Investigaciones Biomédicas, 46010, Valencia, Spain

View Full Text

Author contributions

Disclosures

Received May 2, 2002.
Revision received September 10, 2002.
Accepted September 10, 2002.

This work was supported in part by grants from the Spanish Plan Nacional de Investigación Cientı́fica, Desarrollo e Innovación Tecnológica (SAF97-0001) and from the Promoción General del Conocimiento of Ministerio de Educación y Cultura (PM98-0065 and PM99-0019). P.M. and E.K. are fellows of Generalitat Valenciana.
Correspondence should be addressed to Vicente Felipo, Laboratory of Neurobiology, Instituto de Investigaciones Citológicas, Fundación Valenciana de Investigaciones Biomédicas, Amadeo de Saboya, 4, 46010 Valencia, Spain. E-mail:vfelipo{at}ochoa.fib.es.

Online Impact

Article usage

Select a custom date range for the past year

Article usage: November 2002 to May 2022

	Abstract	Full	Pdf
Nov 2002	255	88	246
Dec 2002	101	167	201
Total 2002	356	255	447
Jan 2003	16	91	84
Feb 2003	7	65	52
Mar 2003	8	45	37
Apr 2003	7	40	30
May 2003	6	23	27
Jun 2003	9	33	18
Jul 2003	5	18	16
Aug 2003	8	18	10
Sep 2003	9	32	26
Oct 2003	9	18	9
Nov 2003	20	29	12
Dec 2003	11	26	22
Total 2003	115	438	343
Jan 2004	14	24	12
Feb 2004	13	10	9
Mar 2004	22	28	15
Apr 2004	14	26	13
May 2004	20	23	15
Jun 2004	10	19	11
Jul 2004	15	29	19
Aug 2004	38	43	10
Sep 2004	40	44	15
Oct 2004	31	41	14
Nov 2004	23	36	24
Dec 2004	18	38	18
Total 2004	258	361	175
Jan 2005	13	18	5
Feb 2005	10	19	6
Mar 2005	19	18	10
Apr 2005	1	11	7
May 2005	9	14	6
Jun 2005	10	15	9
Jul 2005	14	21	6
Aug 2005	7	16	12
Sep 2005	5	5	14
Oct 2005	3	8	10
Nov 2005	12	25	34
Dec 2005	8	10	9
Total 2005	111	180	128
Jan 2006	2	19	11
Feb 2006	5	13	5
Mar 2006	3	14	8
Apr 2006	1	9	9
May 2006	4	16	10
Jun 2006	5	7	6
Jul 2006	3	10	8
Aug 2006	3	8	11
Sep 2006	2	11	12
Oct 2006	5	22	7
Nov 2006	4	15	5
Dec 2006	6	7	4
Total 2006	43	151	96
Jan 2007	3	17	13
Feb 2007	4	8	10
Mar 2007	4	9	10
Apr 2007	3	11	11
May 2007	6	17	9
Jun 2007	5	11	8
Jul 2007	6	10	4
Aug 2007	4	12	7
Sep 2007	4	8	4
Oct 2007	4	17	8
Nov 2007	8	15	12
Dec 2007	7	6	6
Total 2007	58	141	102
Jan 2008	3	11	6
Feb 2008	5	12	8
Mar 2008	8	14	7
Apr 2008	9	14	14
May 2008	8	12	9
Jun 2008	5	10	6
Jul 2008	8	12	6
Aug 2008	16	14	11
Sep 2008	21	12	7
Oct 2008	22	9	8
Nov 2008	16	10	11
Dec 2008	2	5	8
Total 2008	123	135	101
Jan 2009	4	6	4
Feb 2009	7	14	11
Mar 2009	9	11	6
Apr 2009	9	15	10
May 2009	3	31	6
Jun 2009	1	16	3
Jul 2009	4	4	2
Aug 2009	3	6	2
Sep 2009	3	8	5
Oct 2009	4	14	16
Nov 2009	7	10	14
Dec 2009	4	13	16
Total 2009	58	148	95
Jan 2010	7	6	5
Feb 2010	2	11	20
Mar 2010	3	8	8
Apr 2010	4	5	4
May 2010	4	11	7
Jun 2010	4	16	8
Jul 2010	2	11	11
Aug 2010	2	20	12
Sep 2010	1	7	4
Oct 2010	4	13	10
Nov 2010	6	10	10
Dec 2010	4	15	19
Total 2010	43	133	118
Jan 2011	8	8	12
Feb 2011	6	7	5
Mar 2011	9	9	8
Apr 2011	4	8	11
May 2011	9	13	11
Jun 2011	2	6	5
Jul 2011	0	4	5
Aug 2011	11	3	13
Sep 2011	63	9	8
Oct 2011	11	5	8
Nov 2011	7	14	13
Dec 2011	8	10	11
Total 2011	138	96	110
Jan 2012	14	8	7
Feb 2012	7	9	5
Mar 2012	21	13	8
Apr 2012	19	8	6
May 2012	7	7	17
Jun 2012	8	5	9
Jul 2012	8	7	5
Aug 2012	20	5	8
Sep 2012	10	4	10
Oct 2012	14	5	9
Nov 2012	24	5	13
Dec 2012	25	7	7
Total 2012	177	83	104
Jan 2013	18	2	8
Feb 2013	10	3	6
Mar 2013	12	3	11
Apr 2013	15	8	13
May 2013	9	0	16
Jun 2013	4	8	5
Jul 2013	5	1	8
Aug 2013	17	1	5
Sep 2013	0	5	9
Oct 2013	4	6	10
Nov 2013	7	3	5
Dec 2013	4	1	9
Total 2013	105	41	105
Jan 2014	14	9	7
Feb 2014	17	9	12
Mar 2014	8	3	8
Apr 2014	21	5	8
May 2014	11	4	9
Jun 2014	14	3	4
Jul 2014	17	1	8
Aug 2014	4	4	9
Sep 2014	13	4	3
Oct 2014	7	5	12
Nov 2014	13	13	10
Dec 2014	1	2	8
Total 2014	140	62	98
Jan 2015	11	8	10
Feb 2015	7	1	5
Mar 2015	11	7	7
Apr 2015	6	8	20
May 2015	7	5	3
Jun 2015	5	4	8
Jul 2015	4	1	6
Aug 2015	3	6	1
Sep 2015	16	3	5
Oct 2015	3	4	7
Nov 2015	9	7	15
Dec 2015	11	11	9
Total 2015	93	65	96
Jan 2016	10	4	10
Feb 2016	4	10	12
Mar 2016	8	5	17
Apr 2016	4	3	4
May 2016	13	8	4
Jun 2016	10	9	9
Jul 2016	5	3	10
Aug 2016	9	4	5
Sep 2016	7	4	7
Oct 2016	2	3	7
Nov 2016	8	5	4
Dec 2016	7	9	6
Total 2016	87	67	95
Jan 2017	1	10	4
Feb 2017	1	4	2
Mar 2017	5	18	12
Apr 2017	1	10	12
May 2017	2	32	11
Jun 2017	3	9	3
Jul 2017	7	14	14
Aug 2017	0	6	2
Sep 2017	1	6	4
Oct 2017	1	8	3
Nov 2017	1	15	6
Dec 2017	3	5	9
Total 2017	26	137	82
Jan 2018	2	6	8
Feb 2018	0	10	9
Mar 2018	2	9	7
Apr 2018	4	17	12
May 2018	4	17	7
Jun 2018	2	16	5
Jul 2018	5	13	5
Aug 2018	2	4	7
Sep 2018	0	12	8
Oct 2018	0	11	12
Nov 2018	1	18	7
Dec 2018	0	17	8
Total 2018	22	150	95
Jan 2019	3	11	9
Feb 2019	1	7	10
Mar 2019	3	14	11
Apr 2019	2	6	6
May 2019	2	9	10
Jun 2019	2	10	5
Jul 2019	2	7	3
Aug 2019	4	7	6
Sep 2019	7	9	11
Oct 2019	3	6	1
Nov 2019	0	7	14
Dec 2019	2	8	10
Total 2019	31	101	96
Jan 2020	1	5	1
Feb 2020	2	3	3
Mar 2020	1	5	7
Apr 2020	0	3	2
May 2020	1	3	1
Jun 2020	1	2	2
Jul 2020	1	2	3
Aug 2020	1	2	1
Sep 2020	3	10	7
Oct 2020	2	11	14
Nov 2020	3	11	6
Dec 2020	8	23	6
Total 2020	24	80	53
Jan 2021	3	19	10
Feb 2021	0	10	5
Mar 2021	4	23	11
Apr 2021	1	15	5
May 2021	3	20	7
Jun 2021	3	11	1
Jul 2021	1	6	11
Aug 2021	3	17	15
Sep 2021	0	12	7
Oct 2021	2	19	22
Nov 2021	2	16	21
Dec 2021	2	13	3
Total 2021	24	181	118
Jan 2022	1	16	4
Feb 2022	1	11	5
Mar 2022	3	13	4
Apr 2022	0	10	2
May 2022	1	3	5
Total 2022	6	53	20
Total	2038	3058	2677