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ARTICLE, Behavioral/Systems

Lower Sensitivity to Stress and Altered Monoaminergic Neuronal Function in Mice Lacking the NMDA Receptor ε4 Subunit

Yoshiaki Miyamoto, Kiyofumi Yamada, Yukihiro Noda, Hisashi Mori, Masayoshi Mishina and Toshitaka Nabeshima
Journal of Neuroscience 15 March 2002, 22 (6) 2335-2342; https://doi.org/10.1523/JNEUROSCI.22-06-02335.2002
Yoshiaki Miyamoto
1Department of Neuropsychopharmacology and Hospital Pharmacy, Nagoya University Graduate School of Medicine, Showa-ku, Nagoya 466-8560, Japan, and
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Kiyofumi Yamada
1Department of Neuropsychopharmacology and Hospital Pharmacy, Nagoya University Graduate School of Medicine, Showa-ku, Nagoya 466-8560, Japan, and
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Yukihiro Noda
1Department of Neuropsychopharmacology and Hospital Pharmacy, Nagoya University Graduate School of Medicine, Showa-ku, Nagoya 466-8560, Japan, and
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Hisashi Mori
2Department of Molecular Neurobiology and Pharmacology, School of Medicine, University of Tokyo, Bunkyou-Ku, Tokyo 113-0033, Japan
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Masayoshi Mishina
2Department of Molecular Neurobiology and Pharmacology, School of Medicine, University of Tokyo, Bunkyou-Ku, Tokyo 113-0033, Japan
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Toshitaka Nabeshima
1Department of Neuropsychopharmacology and Hospital Pharmacy, Nagoya University Graduate School of Medicine, Showa-ku, Nagoya 466-8560, Japan, and
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Article Information

DOI 
https://doi.org/10.1523/JNEUROSCI.22-06-02335.2002
PubMed 
11896172
Published By 
Society for Neuroscience
History 
  • Received July 31, 2001
  • Revision received November 14, 2001
  • Accepted December 18, 2001
  • First published March 15, 2002.
  • Version of record published March 15, 2002.
Copyright & Usage 
Copyright © 2002 Society for Neuroscience

Author Information

  1. Yoshiaki Miyamoto1,
  2. Kiyofumi Yamada1,
  3. Yukihiro Noda1,
  4. Hisashi Mori2,
  5. Masayoshi Mishina2, and
  6. Toshitaka Nabeshima1
  1. 1Department of Neuropsychopharmacology and Hospital Pharmacy, Nagoya University Graduate School of Medicine, Showa-ku, Nagoya 466-8560, Japan, and
  2. 2Department of Molecular Neurobiology and Pharmacology, School of Medicine, University of Tokyo, Bunkyou-Ku, Tokyo 113-0033, Japan
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Author contributions

Disclosures

    • Received July 31, 2001.
    • Revision received November 14, 2001.
    • Accepted December 18, 2001.
  • This work was supported in part by Grant-in-Aid for Scientific Research 10044260 from the Ministry of Education, Science, Sports, and Culture of Japan and by Special Coordination Funds for Promoting Science and Technology, Target-Oriented Brain Science Research Program from the Ministry of Education, Culture, Sports, Science, and Technology of Japan.

  • Correspondence should be addressed to Dr. Toshitaka Nabeshima, Department of Neuropsychopharmacology and Hospital Pharmacy, Nagoya University Graduate School of Medicine, 65 Tsuruma-cho, Showa-ku, Nagoya 466-8560, Japan. E-mail: tnabeshi{at}med.nagoya-u.ac.jp.

  • Y. Miyamoto's present address: Department of Molecular Genetics, National Institute for Longevity Sciences, Gengo 36-3, Morioka-cho, Oobu, Aichi 474-8522, Japan.

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The Journal of Neuroscience: 22 (6)
Journal of Neuroscience
Vol. 22, Issue 6
15 Mar 2002
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Lower Sensitivity to Stress and Altered Monoaminergic Neuronal Function in Mice Lacking the NMDA Receptor ε4 Subunit
Yoshiaki Miyamoto, Kiyofumi Yamada, Yukihiro Noda, Hisashi Mori, Masayoshi Mishina, Toshitaka Nabeshima
Journal of Neuroscience 15 March 2002, 22 (6) 2335-2342; DOI: 10.1523/JNEUROSCI.22-06-02335.2002

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Lower Sensitivity to Stress and Altered Monoaminergic Neuronal Function in Mice Lacking the NMDA Receptor ε4 Subunit
Yoshiaki Miyamoto, Kiyofumi Yamada, Yukihiro Noda, Hisashi Mori, Masayoshi Mishina, Toshitaka Nabeshima
Journal of Neuroscience 15 March 2002, 22 (6) 2335-2342; DOI: 10.1523/JNEUROSCI.22-06-02335.2002
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Keywords

  • NMDA receptor
  • GluRε4 subunit
  • GluRζ subunit
  • monoaminergic neuronal systems
  • locomotor activity
  • emotional behavior

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