Regulation of GluR1 by the A-Kinase Anchoring Protein 79 (AKAP79) Signaling Complex Shares Properties with Long-Term Depression

This work was supported by grants from the Medical Research Council of Canada (M.C.) and National Institutes of Health Grants NS10202 (S.J.T.), NS35563 (J.W.H), and GM48321 (J.D.S.). We thank Ann Westphal and Jackie Soderling for preparation of the hippocampal cultures and Robert Mouton for preparation of HEK293 cells for biochemical experiments. We thank Gary Westbrook for critical review of this manuscript and Craig Jahr and members of the Scott laboratory for many critical discussions.

Correspondence should be addressed to John D. Scott, Howard Hughes Medical Institute, Vollum Institute, Oregon Health Sciences University, 3181 S.W. Sam Jackson Park Road, Portland, Oregon 97201. E-mail:scott{at}ohsu.edu.

S. J. Tavalin's present address: Department of Pharmacology, University of Tennessee, Health Science Center, Memphis, TN 38163.