Skip to main content

Main menu

  • HOME
  • CONTENT
    • Early Release
    • Featured
    • Current Issue
    • Issue Archive
    • Collections
    • Podcast
  • ALERTS
  • FOR AUTHORS
    • Information for Authors
    • Fees
    • Journal Clubs
    • eLetters
    • Submit
    • Special Collections
  • EDITORIAL BOARD
    • Editorial Board
    • ECR Advisory Board
    • Journal Staff
  • ABOUT
    • Overview
    • Advertise
    • For the Media
    • Rights and Permissions
    • Privacy Policy
    • Feedback
    • Accessibility
  • SUBSCRIBE

User menu

  • Log out
  • Log in
  • My Cart

Search

  • Advanced search
Journal of Neuroscience
  • Log out
  • Log in
  • My Cart
Journal of Neuroscience

Advanced Search

Submit a Manuscript
  • HOME
  • CONTENT
    • Early Release
    • Featured
    • Current Issue
    • Issue Archive
    • Collections
    • Podcast
  • ALERTS
  • FOR AUTHORS
    • Information for Authors
    • Fees
    • Journal Clubs
    • eLetters
    • Submit
    • Special Collections
  • EDITORIAL BOARD
    • Editorial Board
    • ECR Advisory Board
    • Journal Staff
  • ABOUT
    • Overview
    • Advertise
    • For the Media
    • Rights and Permissions
    • Privacy Policy
    • Feedback
    • Accessibility
  • SUBSCRIBE
PreviousNext
Cellular/Molecular

Acid-Sensing Ion Channel 1 Is Localized in Brain Regions with High Synaptic Density and Contributes to Fear Conditioning

John A. Wemmie, Candice C. Askwith, Ejvis Lamani, Martin D. Cassell, John H. Freeman Jr and Michael J. Welsh
Journal of Neuroscience 2 July 2003, 23 (13) 5496-5502; https://doi.org/10.1523/JNEUROSCI.23-13-05496.2003
John A. Wemmie
Departments of 1Psychiatry, 2Physiology and Biophysics, 3Internal Medicine, 4Anatomy and Cell Biology, and 5Psychology, and 6Neuroscience Graduate Program and 7Howard Hughes Medical Institute, University of Iowa, Iowa City, Iowa 52242 and 8Department of Veterans Affairs Medical Center, Iowa City, Iowa 52242
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Candice C. Askwith
Departments of 1Psychiatry, 2Physiology and Biophysics, 3Internal Medicine, 4Anatomy and Cell Biology, and 5Psychology, and 6Neuroscience Graduate Program and 7Howard Hughes Medical Institute, University of Iowa, Iowa City, Iowa 52242 and 8Department of Veterans Affairs Medical Center, Iowa City, Iowa 52242
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Ejvis Lamani
Departments of 1Psychiatry, 2Physiology and Biophysics, 3Internal Medicine, 4Anatomy and Cell Biology, and 5Psychology, and 6Neuroscience Graduate Program and 7Howard Hughes Medical Institute, University of Iowa, Iowa City, Iowa 52242 and 8Department of Veterans Affairs Medical Center, Iowa City, Iowa 52242
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Martin D. Cassell
Departments of 1Psychiatry, 2Physiology and Biophysics, 3Internal Medicine, 4Anatomy and Cell Biology, and 5Psychology, and 6Neuroscience Graduate Program and 7Howard Hughes Medical Institute, University of Iowa, Iowa City, Iowa 52242 and 8Department of Veterans Affairs Medical Center, Iowa City, Iowa 52242
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
John H. Freeman Jr
Departments of 1Psychiatry, 2Physiology and Biophysics, 3Internal Medicine, 4Anatomy and Cell Biology, and 5Psychology, and 6Neuroscience Graduate Program and 7Howard Hughes Medical Institute, University of Iowa, Iowa City, Iowa 52242 and 8Department of Veterans Affairs Medical Center, Iowa City, Iowa 52242
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Michael J. Welsh
Departments of 1Psychiatry, 2Physiology and Biophysics, 3Internal Medicine, 4Anatomy and Cell Biology, and 5Psychology, and 6Neuroscience Graduate Program and 7Howard Hughes Medical Institute, University of Iowa, Iowa City, Iowa 52242 and 8Department of Veterans Affairs Medical Center, Iowa City, Iowa 52242
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • Article
  • Figures & Data
  • Info & Metrics
  • eLetters
  • PDF
Loading

Article Information

DOI 
https://doi.org/10.1523/JNEUROSCI.23-13-05496.2003
PubMed 
12843249
Published By 
Society for Neuroscience
History 
  • Received February 11, 2003
  • Revision received April 23, 2003
  • Accepted April 23, 2003
  • First published July 2, 2003.
  • Version of record published July 2, 2003.
Copyright & Usage 
Copyright © 2003 Society for Neuroscience 0270-6474/03/235496-07.00/0

Author Information

  1. John A. Wemmie1,6,7,8,
  2. Candice C. Askwith3,7,
  3. Ejvis Lamani1,
  4. Martin D. Cassell4,6,
  5. John H. Freeman Jr5,6, and
  6. Michael J. Welsh2,3,6,7
  1. Departments of 1Psychiatry, 2Physiology and Biophysics, 3Internal Medicine, 4Anatomy and Cell Biology, and 5Psychology, and 6Neuroscience Graduate Program and 7Howard Hughes Medical Institute, University of Iowa, Iowa City, Iowa 52242 and 8Department of Veterans Affairs Medical Center, Iowa City, Iowa 52242
View Full Text

Author contributions

Disclosures

    • Received February 11, 2003.
    • Revision received April 23, 2003.
    • Accepted April 23, 2003.
  • This work was supported by the Howard Hughes Medical Institute (HHMI) (M.J.W., J.A.W.), a Veteran's Administration Research Career Development Award (J.A.W.), and National Institute of Neurological Disorders and Stroke Grant NS-38890 (J.H.F.). C.C.A. is an Associate and M.J.W. is an Investigator of the HHMI. We thank the University of Iowa DNA Core Facility (National Institutes of Health Grant DK-25295) for assistance. We thank Melissa Redeker for excellent assistance, Nicholas Pantazis for helpful discussion, Tom Moninger and the Central Microscopy Research Facility for assistance with microscopy and image analysis, and Christine Bromley and the University of Iowa Pathology Research Laboratory for assistance with tissue processing.

  • Correspondence should be addressed to Dr. John A. Wemmie, Department of Psychiatry, University of Iowa, Roy J. and Lucille A. Carver College of Medicine, 500 Eckstein Medical Research Building, Iowa City, IA 52242. E-mail: john-wemmie{at}uiowa.edu.

  • Copyright © 2003 Society for Neuroscience 0270-6474/03/235496-07$15.00/0

Online Impact

 

Article usage

Select a custom date range for the past year
E.g., 2025-06-16
to
E.g., 2025-06-16

Article usage: January 2018 to June 2025

AbstractFullPdf
Jan 201862422
Feb 2018173022
Mar 2018113119
Apr 201873022
May 201873728
Jun 201874527
Jul 201812219
Aug 20182438
Sep 201844518
Oct 201873112
Nov 201833114
Dec 2018103925
Total 201882408236
Jan 201942715
Feb 201943010
Mar 201932918
Apr 201972616
May 2019143724
Jun 201974429
Jul 201923917
Aug 201982926
Oct 2019114512
Nov 20193158
Dec 201912312
Total 201964344187
Jan 20206415
Feb 20208307
Mar 20206209
May 202031214
Jun 202031214
Jul 20205158
Aug 2020195
Sep 202011960
Oct 202032550
Nov 202054113
Dec 202075414
Total 202048278199
Jan 202189418
Feb 202175318
Mar 202193723
Apr 20217145
May 202145813
Jun 2021134723
Jul 2021112220
Aug 202143930
Sep 202163021
Oct 202145626
Nov 202124528
Dec 2021102614
Total 202185521239
Jan 202242510
Feb 20226209
Mar 2022121815
Apr 202272910
May 202295215
Jun 202263419
Jul 202252911
Aug 202252710
Sep 202263615
Oct 202292314
Nov 20224100
Dec 20220116
Total 202273314134
Jan 2023134817
Feb 202352516
Mar 2023147812
Apr 202382420
May 202382316
Jun 20237156
Jul 2023102323
Aug 202372210
Sep 202372812
Oct 202352317
Nov 202382913
Dec 202393915
Total 2023101377177
Jan 2024135216
Feb 202484316
Mar 2024153329
Apr 202493416
May 2024728817
Jun 202442717
Jul 202495422
Aug 202463715
Sep 2024113013
Oct 202413215
Nov 202433519
Dec 202435116
Total 202489716211
Jan 202545125
Feb 2025611813
Mar 202529825
Apr 202573113
May 202524323
Jun 20251513
Total 202522346112
Total56433041495
Back to top

In this issue

The Journal of Neuroscience: 23 (13)
Journal of Neuroscience
Vol. 23, Issue 13
2 Jul 2003
  • Table of Contents
  • About the Cover
  • Index by author
Email

Thank you for sharing this Journal of Neuroscience article.

NOTE: We request your email address only to inform the recipient that it was you who recommended this article, and that it is not junk mail. We do not retain these email addresses.

Enter multiple addresses on separate lines or separate them with commas.
Acid-Sensing Ion Channel 1 Is Localized in Brain Regions with High Synaptic Density and Contributes to Fear Conditioning
(Your Name) has forwarded a page to you from Journal of Neuroscience
(Your Name) thought you would be interested in this article in Journal of Neuroscience.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Print
View Full Page PDF
Citation Tools
Acid-Sensing Ion Channel 1 Is Localized in Brain Regions with High Synaptic Density and Contributes to Fear Conditioning
John A. Wemmie, Candice C. Askwith, Ejvis Lamani, Martin D. Cassell, John H. Freeman Jr, Michael J. Welsh
Journal of Neuroscience 2 July 2003, 23 (13) 5496-5502; DOI: 10.1523/JNEUROSCI.23-13-05496.2003

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
Respond to this article
Request Permissions
Share
Acid-Sensing Ion Channel 1 Is Localized in Brain Regions with High Synaptic Density and Contributes to Fear Conditioning
John A. Wemmie, Candice C. Askwith, Ejvis Lamani, Martin D. Cassell, John H. Freeman Jr, Michael J. Welsh
Journal of Neuroscience 2 July 2003, 23 (13) 5496-5502; DOI: 10.1523/JNEUROSCI.23-13-05496.2003
Twitter logo Facebook logo Mendeley logo
  • Tweet Widget
  • Facebook Like
  • Google Plus One

Jump to section

  • Article
    • Abstract
    • Introduction
    • Materials and Methods
    • Results and Discussion
    • Conclusions
    • Footnotes
    • References
  • Figures & Data
  • Info & Metrics
  • eLetters
  • PDF

Keywords

  • ASIC1
  • localization
  • CNS
  • fear conditioning
  • emotion
  • learning, memory

Responses to this article

Respond to this article

Jump to comment:

No eLetters have been published for this article.

Related Articles

Cited By...

More in this TOC Section

  • CXCL12 Engages Cortical Inhibitory Neurons to Enhance Dendritic Spine Plasticity and Structured Network Activity
  • Atypical Cadherin FAT2 Is Required for Synaptic Integrity and Motor Behaviors
  • Sex Differences in Histamine Regulation of Striatal Dopamine
Show more Cellular/Molecular
  • Home
  • Alerts
  • Follow SFN on BlueSky
  • Visit Society for Neuroscience on Facebook
  • Follow Society for Neuroscience on Twitter
  • Follow Society for Neuroscience on LinkedIn
  • Visit Society for Neuroscience on Youtube
  • Follow our RSS feeds

Content

  • Early Release
  • Current Issue
  • Issue Archive
  • Collections

Information

  • For Authors
  • For Advertisers
  • For the Media
  • For Subscribers

About

  • About the Journal
  • Editorial Board
  • Privacy Notice
  • Contact
  • Accessibility
(JNeurosci logo)
(SfN logo)

Copyright © 2025 by the Society for Neuroscience.
JNeurosci Online ISSN: 1529-2401

The ideas and opinions expressed in JNeurosci do not necessarily reflect those of SfN or the JNeurosci Editorial Board. Publication of an advertisement or other product mention in JNeurosci should not be construed as an endorsement of the manufacturer’s claims. SfN does not assume any responsibility for any injury and/or damage to persons or property arising from or related to any use of any material contained in JNeurosci.