Possible Involvement of P2Y₂ Metabotropic Receptors in ATP-Induced Transient Receptor Potential Vanilloid Receptor 1-Mediated Thermal Hypersensitivity

1Department of Cellular and Molecular Physiology, Mie University School of Medicine, Tsu, Mie 514-8507, Japan, 2Inoue Foundation for Science, Tokyo 150-0033, Japan, 3Department of Anatomy and Neuroscience, Hyogo College of Medicine, Hyogo 663-8501, Japan, 4Institute of Laboratory Animals, Mie University, Tsu, Mie 514-8507, 5Institut National de la Santé et de la Recherche Médicale Unité 311, 67065 Strasbourg, France, 6Division of Biosignaling, National Institute of Health Sciences, Tokyo 158-8501, and 7Department of Molecular and System Pharmacology, Graduate School of Pharmaceutical Sciences, Kyushu University, Fukuoka 812-8582, Japan

1Department of Cellular and Molecular Physiology, Mie University School of Medicine, Tsu, Mie 514-8507, Japan, 2Inoue Foundation for Science, Tokyo 150-0033, Japan, 3Department of Anatomy and Neuroscience, Hyogo College of Medicine, Hyogo 663-8501, Japan, 4Institute of Laboratory Animals, Mie University, Tsu, Mie 514-8507, 5Institut National de la Santé et de la Recherche Médicale Unité 311, 67065 Strasbourg, France, 6Division of Biosignaling, National Institute of Health Sciences, Tokyo 158-8501, and 7Department of Molecular and System Pharmacology, Graduate School of Pharmaceutical Sciences, Kyushu University, Fukuoka 812-8582, Japan

1Department of Cellular and Molecular Physiology, Mie University School of Medicine, Tsu, Mie 514-8507, Japan, 2Inoue Foundation for Science, Tokyo 150-0033, Japan, 3Department of Anatomy and Neuroscience, Hyogo College of Medicine, Hyogo 663-8501, Japan, 4Institute of Laboratory Animals, Mie University, Tsu, Mie 514-8507, 5Institut National de la Santé et de la Recherche Médicale Unité 311, 67065 Strasbourg, France, 6Division of Biosignaling, National Institute of Health Sciences, Tokyo 158-8501, and 7Department of Molecular and System Pharmacology, Graduate School of Pharmaceutical Sciences, Kyushu University, Fukuoka 812-8582, Japan

1Department of Cellular and Molecular Physiology, Mie University School of Medicine, Tsu, Mie 514-8507, Japan, 2Inoue Foundation for Science, Tokyo 150-0033, Japan, 3Department of Anatomy and Neuroscience, Hyogo College of Medicine, Hyogo 663-8501, Japan, 4Institute of Laboratory Animals, Mie University, Tsu, Mie 514-8507, 5Institut National de la Santé et de la Recherche Médicale Unité 311, 67065 Strasbourg, France, 6Division of Biosignaling, National Institute of Health Sciences, Tokyo 158-8501, and 7Department of Molecular and System Pharmacology, Graduate School of Pharmaceutical Sciences, Kyushu University, Fukuoka 812-8582, Japan

1Department of Cellular and Molecular Physiology, Mie University School of Medicine, Tsu, Mie 514-8507, Japan, 2Inoue Foundation for Science, Tokyo 150-0033, Japan, 3Department of Anatomy and Neuroscience, Hyogo College of Medicine, Hyogo 663-8501, Japan, 4Institute of Laboratory Animals, Mie University, Tsu, Mie 514-8507, 5Institut National de la Santé et de la Recherche Médicale Unité 311, 67065 Strasbourg, France, 6Division of Biosignaling, National Institute of Health Sciences, Tokyo 158-8501, and 7Department of Molecular and System Pharmacology, Graduate School of Pharmaceutical Sciences, Kyushu University, Fukuoka 812-8582, Japan

1Department of Cellular and Molecular Physiology, Mie University School of Medicine, Tsu, Mie 514-8507, Japan, 2Inoue Foundation for Science, Tokyo 150-0033, Japan, 3Department of Anatomy and Neuroscience, Hyogo College of Medicine, Hyogo 663-8501, Japan, 4Institute of Laboratory Animals, Mie University, Tsu, Mie 514-8507, 5Institut National de la Santé et de la Recherche Médicale Unité 311, 67065 Strasbourg, France, 6Division of Biosignaling, National Institute of Health Sciences, Tokyo 158-8501, and 7Department of Molecular and System Pharmacology, Graduate School of Pharmaceutical Sciences, Kyushu University, Fukuoka 812-8582, Japan

1Department of Cellular and Molecular Physiology, Mie University School of Medicine, Tsu, Mie 514-8507, Japan, 2Inoue Foundation for Science, Tokyo 150-0033, Japan, 3Department of Anatomy and Neuroscience, Hyogo College of Medicine, Hyogo 663-8501, Japan, 4Institute of Laboratory Animals, Mie University, Tsu, Mie 514-8507, 5Institut National de la Santé et de la Recherche Médicale Unité 311, 67065 Strasbourg, France, 6Division of Biosignaling, National Institute of Health Sciences, Tokyo 158-8501, and 7Department of Molecular and System Pharmacology, Graduate School of Pharmaceutical Sciences, Kyushu University, Fukuoka 812-8582, Japan

1Department of Cellular and Molecular Physiology, Mie University School of Medicine, Tsu, Mie 514-8507, Japan, 2Inoue Foundation for Science, Tokyo 150-0033, Japan, 3Department of Anatomy and Neuroscience, Hyogo College of Medicine, Hyogo 663-8501, Japan, 4Institute of Laboratory Animals, Mie University, Tsu, Mie 514-8507, 5Institut National de la Santé et de la Recherche Médicale Unité 311, 67065 Strasbourg, France, 6Division of Biosignaling, National Institute of Health Sciences, Tokyo 158-8501, and 7Department of Molecular and System Pharmacology, Graduate School of Pharmaceutical Sciences, Kyushu University, Fukuoka 812-8582, Japan

1Department of Cellular and Molecular Physiology, Mie University School of Medicine, Tsu, Mie 514-8507, Japan, 2Inoue Foundation for Science, Tokyo 150-0033, Japan, 3Department of Anatomy and Neuroscience, Hyogo College of Medicine, Hyogo 663-8501, Japan, 4Institute of Laboratory Animals, Mie University, Tsu, Mie 514-8507, 5Institut National de la Santé et de la Recherche Médicale Unité 311, 67065 Strasbourg, France, 6Division of Biosignaling, National Institute of Health Sciences, Tokyo 158-8501, and 7Department of Molecular and System Pharmacology, Graduate School of Pharmaceutical Sciences, Kyushu University, Fukuoka 812-8582, Japan

1Department of Cellular and Molecular Physiology, Mie University School of Medicine, Tsu, Mie 514-8507, Japan, 2Inoue Foundation for Science, Tokyo 150-0033, Japan, 3Department of Anatomy and Neuroscience, Hyogo College of Medicine, Hyogo 663-8501, Japan, 4Institute of Laboratory Animals, Mie University, Tsu, Mie 514-8507, 5Institut National de la Santé et de la Recherche Médicale Unité 311, 67065 Strasbourg, France, 6Division of Biosignaling, National Institute of Health Sciences, Tokyo 158-8501, and 7Department of Molecular and System Pharmacology, Graduate School of Pharmaceutical Sciences, Kyushu University, Fukuoka 812-8582, Japan

1Department of Cellular and Molecular Physiology, Mie University School of Medicine, Tsu, Mie 514-8507, Japan, 2Inoue Foundation for Science, Tokyo 150-0033, Japan, 3Department of Anatomy and Neuroscience, Hyogo College of Medicine, Hyogo 663-8501, Japan, 4Institute of Laboratory Animals, Mie University, Tsu, Mie 514-8507, 5Institut National de la Santé et de la Recherche Médicale Unité 311, 67065 Strasbourg, France, 6Division of Biosignaling, National Institute of Health Sciences, Tokyo 158-8501, and 7Department of Molecular and System Pharmacology, Graduate School of Pharmaceutical Sciences, Kyushu University, Fukuoka 812-8582, Japan

1Department of Cellular and Molecular Physiology, Mie University School of Medicine, Tsu, Mie 514-8507, Japan, 2Inoue Foundation for Science, Tokyo 150-0033, Japan, 3Department of Anatomy and Neuroscience, Hyogo College of Medicine, Hyogo 663-8501, Japan, 4Institute of Laboratory Animals, Mie University, Tsu, Mie 514-8507, 5Institut National de la Santé et de la Recherche Médicale Unité 311, 67065 Strasbourg, France, 6Division of Biosignaling, National Institute of Health Sciences, Tokyo 158-8501, and 7Department of Molecular and System Pharmacology, Graduate School of Pharmaceutical Sciences, Kyushu University, Fukuoka 812-8582, Japan