Figure 3. Arc mRNA levels return to baseline at different rates across regions. A, Post hoc analysis of autoradiographic data for regions of interest in section 2 (outlined in Fig. 1 B) of home-caged controls (HC; n = 5), newly trained animals killed 30 min (NT; n = 5) or 60 min (NT-60; n = 5) after the session, and overtrained animals (OT) killed 30 min after their eighth session (OT; n = 5). The inset at top right shows overall group mean 35S cpm ± SEM. B, Additional regions of interest from sections 1 and 3-4 (outlined in Fig. 1 A, C-D). Data were plotted as mean 35S cpm ± SEM. LIM, Infra/prelimbic cortex; SOM, somatosensory cortex; PERI, perirhinal cortex; ENT, entorhinal cortex; SUB, subiculum; CPu, caudate-putamen; ACC, anterior cingulate cortex; PIR, piriform cortex; INS, insular cortex; CeA, central nucleus of the amygdala. Post hoc analysis by Student-Newman-Keuls: significant increase, # versus HC, OT, and NT-60; * versus HC, @ versus NT-60, p < 0.05-p < 0.001.