Cover picture: Dendritic filopodia are protrusions of immature neurons that may be important in dendritic growth and branching, synaptogenesis, and spine formation. The image shows two movie sequences of a dendritic growth cone from a pyramidal neuron at postnatal day 2, before (left film strip) and after (right film strip) focal glutamate application. Glutamate induces elongation of many shaft filopodia. In this issue (pages 7129–7142). also present evidence supporting the existence of two different populations of filopodia in dendritic growth cones and shafts that are differentially regulated by neuronal activity.