Figure 3. ATPγS modulation of evoked and spontaneous EPSCs at interneuron synapses. A-D, Data for ATPγS application during recordings from interneurons. A, Evoked EPSCs; B, sEPSC amplitude; C, sEPSC frequency recorded simultaneously before, during, and after ATPγS application for one representative neuron. D, Representative sEPSCs. A, Inset, Representative evoked EPSCs. In each case, the bar graphs to the right show average data from all experiments of this type. In all these cases, after washing out ATPγS(∼10-20 min), we applied l-AP-4, and the effect of this agonist is illustrated in E-H. E, Evoked EPSCs; F, sEPSC amplitude; G, sEPSC frequency before, during, and after l-AP-4 application for one representative neuron. H, Representative sEPSCs. E, Inset, Representative evoked EPSCs. In each case, the bar graphs to the right show average data from all experiments of this type. a, i, b, i, c, iii, Before, during, and after agonist application, respectively.