Cover picture: Presynaptic uptake of choline by the hemicholinium-3-sensitive choline transporter (CHT) is a critical step preceding neuronal acetylcholine synthesis. Consistent with this link between CHT function and neurotransmitter synthesis, CHT-specific antibodies stain presynaptic arborizations (red) that α-bungarotoxin-labeled nicotinic acetylcholine receptors clustered on the underlying muscle (green) at neuromuscular junctions of the mouse diaphragm. (This image is courtesy of Valentina Savchenko.) For details, see the article by Ferguson et al. in this issue (pages 9697–9709).