About the Cover
Cover image
Cover picture: Dynamic changes in place cell firing and water maze performance after a flurothylinduced generalized tonicrow, Before the seizure a place cell (left column) fires maximally at 11:00. High firing rates are represented by purple and green pixels. A theta cell fires in all locations of the field (middle column). The right column shows the swimming path to the escape platform. The rat had previously been trained to find the platform. Second row, Twenty minutes after a brief seizure, the place cell stops firing and the rat swims around the perimeter of the tank and cannot locate the platform. Note that the theta cell continues to fire. Third row, One hour after the seizure, some place cells begin to fire, although the place cell shown has little activity. The rat is able to find the platform, although more slowly than before the seizure. Bottom row, Two hours after the seizure, the place cell is firing and the animal quickly swims to the platform. For details, see the article by Liu et al. in this issue (pages 11505–11515).