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Cellular/Molecular

Activity-Dependent Redistribution and Essential Role of Cortactin in Dendritic Spine Morphogenesis

Heike Hering and Morgan Sheng
Journal of Neuroscience 17 December 2003, 23 (37) 11759-11769; DOI: https://doi.org/10.1523/JNEUROSCI.23-37-11759.2003
Heike Hering
The Picower Center for Learning and Memory, Howard Hughes Medical Institute, RIKEN-MIT Neuroscience Research Center, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139
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Morgan Sheng
The Picower Center for Learning and Memory, Howard Hughes Medical Institute, RIKEN-MIT Neuroscience Research Center, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139
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Article Information

DOI 
https://doi.org/10.1523/JNEUROSCI.23-37-11759.2003
PubMed 
14684878
Published By 
Society for Neuroscience
History 
  • Received September 2, 2003
  • Revision received October 22, 2003
  • Accepted October 24, 2003
  • First published December 18, 2003.
  • Version of record published December 18, 2003.
Copyright & Usage 
Copyright © 2003 Society for Neuroscience 0270-6474/03/2311759-11.00/0

Author Information

  1. Heike Hering and
  2. Morgan Sheng
  1. The Picower Center for Learning and Memory, Howard Hughes Medical Institute, RIKEN-MIT Neuroscience Research Center, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139
View Full Text

Author contributions

Disclosures

    • Received September 2, 2003.
    • Revision received October 22, 2003.
    • Accepted October 24, 2003.
  • M.S. is an Investigator of the Howard Hughes Medical Institute. The GAD-6 monoclonal antibody developed by David Gottlieb was obtained from the Developmental Studies Hybridoma Bank developed under the auspices of the National Institute of Child Health and Human Development and maintained by the University of Iowa, Department of Biological Sciences, Iowa City, IA 52242. We thank Sheila Rudolph-Correia for excellent technical assistance and the following for reagents: Sondra Schlesinger for the pSinRep5, J. Thomas Parson for murine cortactin cDNA, and Xi Zhan for clone pJP20. We are grateful to Carlo Sala and Terunaga Nakagawa for unpublished reagents.

  • Correspondence should be addressed to Morgan Sheng, Picower Center for Learning and Memory, Massachusetts Institute of Technology, 77 Massachusetts Avenue (E18-215), Cambridge, MA 02139. E-mail: msheng{at}mit.edu.

  • Copyright © 2003 Society for Neuroscience 0270-6474/03/2311759-11$15.00/0

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AbstractFullPdf
Dec 2003521193602
Total 2003521193602
Jan 2004173498533
Feb 200434302240
Mar 200440267195
Apr 200419196126
May 200418177108
Jun 20041918293
Jul 20042812763
Aug 20044315161
Sep 20043411149
Oct 2004189949
Nov 20041513182
Dec 2004217357
Total 200446223141656
Jan 2005119367
Feb 2005159056
Mar 2005289753
Apr 200556832
May 2005198057
Jun 2005188572
Jul 2005148772
Aug 200588741
Sep 200566838
Oct 200557038
Nov 2005178339
Dec 200566028
Total 2005152968593
Jan 2006127240
Feb 2006115430
Mar 200646841
Apr 200634041
May 200697349
Jun 200663937
Jul 200654635
Aug 200654425
Sep 200684027
Oct 2006115528
Nov 2006104519
Dec 200643827
Total 200688614399
Jan 200773722
Feb 200785934
Mar 200794228
Apr 2007104428
May 200764134
Jun 2007104230
Jul 2007122831
Aug 200793117
Sep 200772818
Oct 2007114127
Nov 200794126
Dec 200763420
Total 2007104468315
Jan 200852813
Feb 2008112920
Mar 2008102824
Apr 200832416
May 200872916
Jun 2008142613
Jul 2008155848
Aug 2008163321
Sep 2008203828
Oct 2008193728
Nov 2008174225
Dec 2008111618
Total 2008148388270
Jan 2009133525
Feb 2009153923
Mar 2009263123
Apr 2009173428
May 2009163628
Jun 2009134345
Jul 2009165230
Aug 2009172731
Sep 200953432
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Total 2009170409335
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Feb 201051920
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Apr 20102208
May 201083223
Jun 2010102832
Jul 2010344024
Aug 2010113937
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Total 2010126325260
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Feb 201162116
Mar 2011191914
Apr 2011111818
May 201119159
Jun 201192114
Jul 201182114
Aug 201181518
Sep 201192226
Oct 2011223827
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Dec 201151118
Total 2011137239213
Jan 2012174925
Feb 2012111815
Mar 2012152426
Apr 2012193623
May 201292317
Jun 2012131923
Jul 2012132320
Aug 2012111717
Sep 2012122223
Oct 2012182937
Nov 2012323435
Dec 2012291421
Total 2012199308282
Jan 2013121429
Feb 2013142121
Mar 2013302136
Apr 201391624
May 2013121122
Jun 201351019
Jul 201311744
Aug 2013111518
Sep 2013101527
Oct 201381834
Nov 2013191124
Dec 2013111022
Total 2013152169320
Jan 2014202919
Feb 2014181021
Mar 2014131023
Apr 2014332526
May 2014202123
Jun 2014162018
Jul 2014171414
Aug 2014101217
Sep 201461519
Oct 201461516
Nov 2014111116
Dec 201421215
Total 2014172194227
Jan 2015101720
Feb 201591631
Mar 2015112128
Apr 20159518
May 2015101419
Jun 2015151436
Jul 201531517
Aug 20157822
Sep 20152811
Oct 201550924
Nov 2015101620
Dec 2015141211
Total 2015150155257
Jan 2016152528
Feb 201619726
Mar 2016111836
Apr 201661312
May 201652125
Jun 2016121824
Jul 2016144932
Aug 201616721
Sep 2016211415
Oct 20164164
Nov 201663121
Dec 201602516
Total 2016129244260
Jan 201743078
Feb 201702824
Mar 201704812
Apr 20172149
May 201737718
Jun 201742211
Jul 20172248
Aug 20174145
Sep 20171106
Oct 201793813
Nov 20171208
Dec 201722113
Total 201732623135
Jan 20183114
Feb 201812212
Mar 201811812
Apr 201853117
May 201822311
Jun 20182246
Jul 20182229
Aug 20183165
Sep 20181309
Oct 201812712
Nov 20183226
Dec 20181236
Total 201825269109
Jan 201952210
Feb 20193197
Mar 201931815
Apr 20191178
May 201932917
Jun 201952614
Jul 20191199
Aug 201906419
Sep 201931349
Oct 2019322610
Nov 201932713
Dec 20192208
Total 201932621139
Jan 202042915
Feb 202011511
Mar 202041520
Apr 20202113
May 202002712
Jun 2020268
Jul 20203208
Aug 2020095
Sep 202082913
Oct 202062516
Nov 202073112
Dec 20203268
Total 202040243131
Jan 2021144611
Feb 20211273
Mar 2021030
Total 2021157614
Total285488206517
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In this issue

The Journal of Neuroscience: 23 (37)
Journal of Neuroscience
Vol. 23, Issue 37
17 Dec 2003
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Activity-Dependent Redistribution and Essential Role of Cortactin in Dendritic Spine Morphogenesis
Heike Hering, Morgan Sheng
Journal of Neuroscience 17 December 2003, 23 (37) 11759-11769; DOI: 10.1523/JNEUROSCI.23-37-11759.2003

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Activity-Dependent Redistribution and Essential Role of Cortactin in Dendritic Spine Morphogenesis
Heike Hering, Morgan Sheng
Journal of Neuroscience 17 December 2003, 23 (37) 11759-11769; DOI: 10.1523/JNEUROSCI.23-37-11759.2003
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Keywords

  • actin
  • hippocampal neuron
  • NMDA receptor
  • spine
  • live imaging
  • RNA interference

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