Increased Seizure Susceptibility and Proconvulsant Activity of Anandamide in Mice Lacking Fatty Acid Amide Hydrolase

This work was supported by National Institute of Drug Abuse of the National Institutes of Health Grants DA13173 and DA15197, Allergan, Inc., the Helen L. Dorris Institute for the Study of Neurological and Psychiatric Disorders of Children and Adolescents, and the Skaggs Institute for Chemical Biology. We thank Tamas Bartfai, Floyd Bloom, and the entire Cravatt group for helpful discussions and critical analysis of the work described in this manuscript.

Correspondence should be addressed to Dr. Benjamin F. Cravatt, 10550 North Torrey Pines Road, La Jolla, CA 92037. E-mail:cravatt{at}scripps.edu.