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ARTICLE, Behavioral/Systems/Cognitive

Increased Seizure Susceptibility and Proconvulsant Activity of Anandamide in Mice Lacking Fatty Acid Amide Hydrolase

Angela B. Clement, E. Gregory Hawkins, Aron H. Lichtman and Benjamin F. Cravatt
Journal of Neuroscience 1 May 2003, 23 (9) 3916-3923; DOI: https://doi.org/10.1523/JNEUROSCI.23-09-03916.2003
Angela B. Clement
1The Skaggs Institute for Chemical Biology and Departments of Cell Biology and Chemistry, The Scripps Research Institute, La Jolla, California 92037, and
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E. Gregory Hawkins
1The Skaggs Institute for Chemical Biology and Departments of Cell Biology and Chemistry, The Scripps Research Institute, La Jolla, California 92037, and
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Aron H. Lichtman
2Department of Pharmacology and Toxicology, Medical College of Virginia Campus, Virginia Commonwealth University, Richmond, Virginia 23298
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Benjamin F. Cravatt
1The Skaggs Institute for Chemical Biology and Departments of Cell Biology and Chemistry, The Scripps Research Institute, La Jolla, California 92037, and
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The Journal of Neuroscience: 23 (9)
Journal of Neuroscience
Vol. 23, Issue 9
1 May 2003
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Increased Seizure Susceptibility and Proconvulsant Activity of Anandamide in Mice Lacking Fatty Acid Amide Hydrolase
Angela B. Clement, E. Gregory Hawkins, Aron H. Lichtman, Benjamin F. Cravatt
Journal of Neuroscience 1 May 2003, 23 (9) 3916-3923; DOI: 10.1523/JNEUROSCI.23-09-03916.2003

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Increased Seizure Susceptibility and Proconvulsant Activity of Anandamide in Mice Lacking Fatty Acid Amide Hydrolase
Angela B. Clement, E. Gregory Hawkins, Aron H. Lichtman, Benjamin F. Cravatt
Journal of Neuroscience 1 May 2003, 23 (9) 3916-3923; DOI: 10.1523/JNEUROSCI.23-09-03916.2003
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Keywords

  • anandamide
  • bicuculline
  • CB1 receptor
  • endocannabinoid
  • epilepsy
  • excitotoxicity
  • fatty acid amide hydrolase
  • kainate
  • seizure

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