In the article “Reduced Expression of P2Y1 Receptors in Connexin43-Null Mice Alters Calcium Signaling and Migration of Neural Progenitor Cells,” by Eliana Scemes, Nathalie Duval, and Paolo Meda, which appeared on pages 11444-11452 of the December 10, 2003 issue, the wrong version of Figure 4 was used. The correct version of Figure 4, as well as the legend, is printed here.
P2Y1 and P2X7 receptors participate in spontaneous calcium oscillations of WT and Cx43-null neural progenitors. A, Wild-type neural progenitor calcium transients induced by bath application of 30 μm 2-MeS-ATP (2-Mes; arrow) were totally prevented by the specific P2Y1R antagonist MRS-2179 (MRS; 5 μm). B, The potent P2X7R antagonist KN62 (1 μm) blocked calcium transient induced by 100 μm BzATP in Cx43-null progenitors. Spontaneous intracellular calcium oscillations recorded from fura-2 AM-loaded (2.5 μm) WT (C) and Cx43-null (D) neural progenitors were prevented by bath application of 5 μm MRS-2179 and 1 μm KN62, respectively. The oscillations of each cell are represented by black and gray traces.
