Figure 4.
Effects of β-FNA on learning 11 d after injection. Escape latencies (A), distance traveled (B), and swim speeds (C) during reversal training for the animals treated with β-FNA (solid circles) and saline (open squares). D, The percentage of time spent in the correct quadrant was determined (means ± SEM) during reversal probe trials on days 11, 13, and 15. Escape latency (E), distance traveled (F), and swim speed (G) for a separate group of animals trained in the water maze for 5 consecutive days starting 11 d after injection. Spatial probe trials were given after the first, third, and fifth day of training. H, The percentage of time spent in the correct quadrant during the during the probe trials and on the first trial of day 1. The dashed line represents chance performance levels (25%). Significant differences were found. #p = 0.005 versus trial 1; *p = 0.001 versus saline control.