β-Amyloid Peptides Induce Mitochondrial Dysfunction and Oxidative Stress in Astrocytes and Death of Neurons through Activation of NADPH Oxidase

This work was supported by the Wellcome Trust, The Medical Research Council, and the Miriam Marks Fund. We especially thank Dr. Jake Jacobson for invaluable suggestions and discussion while the work was in progress, and we thank Professors John Clark, Stephen Bolsover, and Rosario Rizzuto for helpful discussion and comments on this manuscript.

Correspondence should be addressed to Michael R. Duchen, Department of Physiology, University College London, Gower Street, London WC1E 6BT, UK. E-mail: m.duchen{at}ucl.ac.uk.

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