Cover picture: Proper development of sympathetic innervation of the gastrointestinal tract is critical for its function. Whole-mount tyrosine hydroxylase immunostaining of the mouse gastrointestinal tract reveals the extent of perinatal sympathetic innervation, with sympathetic axons traveling along mesenteric arterial vasculature supplying blood to the intestines. NGF plays a crucial role in the development of this intricate pattern of sympathetic target innervation independently of its requirement for neuron survival. For details, see the article by Glebova and Ginty in this issue (pages 743–751).