Skip to main content

Umbrella menu

  • SfN.org
  • eNeuro
  • The Journal of Neuroscience
  • Neuronline
  • BrainFacts.org

Main menu

  • HOME
  • CONTENT
    • Early Release
    • Featured
    • Current Issue
    • Issue Archive
    • Collections
  • ALERTS
  • FOR AUTHORS
    • Preparing a Manuscript
    • Submission Guidelines
    • Fees
    • Journal Club
    • eLetters
    • Submit
  • EDITORIAL BOARD
  • ABOUT
    • Overview
    • Advertise
    • For the Media
    • Rights and Permissions
    • Privacy Policy
    • Feedback
  • SUBSCRIBE
  • SfN.org
  • eNeuro
  • The Journal of Neuroscience
  • Neuronline
  • BrainFacts.org

User menu

  • Log in
  • Subscribe
  • My alerts
  • My Cart

Search

  • Advanced search
Journal of Neuroscience
  • Log in
  • Subscribe
  • My alerts
  • My Cart
Journal of Neuroscience

Advanced Search

Submit a Manuscript
  • HOME
  • CONTENT
    • Early Release
    • Featured
    • Current Issue
    • Issue Archive
    • Collections
  • ALERTS
  • FOR AUTHORS
    • Preparing a Manuscript
    • Submission Guidelines
    • Fees
    • Journal Club
    • eLetters
    • Submit
  • EDITORIAL BOARD
  • ABOUT
    • Overview
    • Advertise
    • For the Media
    • Rights and Permissions
    • Privacy Policy
    • Feedback
  • SUBSCRIBE
PreviousNext
BRIEF COMMUNICATIONS

Olfaction in Olfactory Bulbectomized Rats

Burton Slotnick, Renee Cockerham and Erin Pickett
Journal of Neuroscience 13 October 2004, 24 (41) 9195-9200; DOI: https://doi.org/10.1523/JNEUROSCI.1936-04.2004
Burton Slotnick
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Renee Cockerham
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Erin Pickett
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • Article
  • Figures & Data
  • Info & Metrics
  • eLetters
  • PDF
Loading

Article Figures & Data

Figures

  • Tables
  • Figure 1.
    • Download figure
    • Open in new tab
    • Download powerpoint
    Figure 1.

    Top, Photograph showing the extended forebrain on the right (neonatally operated) hemisphere. The forebrain extension filled the cavity vacated by the neonatal bulbectomy. Frontal levels A, B, and C are approximately those illustrated in photomicrographs A-C. A-C, Photomicrographs of sections through the anterior (A) and middle (B) portion of the forebrain extension and through the rostral anterior olfactory nucleus (C). As shown, the extended forebrain tissue is heavily invested with WGA-HRP reaction product, and numerous glomerular-like clusters can be identified within the anterior olfactory nucleus. D, Higher-magnification photomicrograph of region outlined in C showing details of glomerular-like clusters of axons within the anterior olfactory nucleus.

  • Figure 2.
    • Download figure
    • Open in new tab
    • Download powerpoint
    Figure 2.

    A, Photomicrograph of a section through the frontal cortex and posterior aspect of the anterior olfactory nucleus in another experimental rat. The dense WGA-HRP reaction product in the AON is representative of that found in most NBXi rats that could detect and discriminate odors. B, Photomicrograph (using polarized light optics) showing a stream of fibers directed toward ependyma juxtaposed to the anterior limb of the anterior commissure and fibers entering this zone (C).

  • Figure 3.
    • Download figure
    • Open in new tab
    • Download powerpoint
    Figure 3.

    Mean performance of nosmic NBXi rats, control rats, and rats with olfactory bulb remnants on odor detection tasks (top left graph) and odor discrimination tasks (top right graph). In odor detection tasks A, B, C, D, and E, the S+ stimulus was jasmine perfume, citral, 10% and 1% acetic acid, and (+)-carvone, respectively (see Materials and Methods). Each data point is the mean score on a block of 20 trials. The bottom graphs show performance of the two NBXi rats that performed best (rats AA1 and EE1) and one rat (AA5) representative of those that performed more poorly on the odor detection and discrimination tasks.

Tables

  • Figures
    • View popup
    Table 1.

    Total errors in a 200 trial session or errors to criterion of 85% correct responding for each of the experimental rats that could detect odors and mean scores for controls on each odor detection and discrimination task

    Rat number EA 5%a EA 1% EA 0.1% EA 0.01% A B C D E D1 D2 D3 D4
    AA1 14 0 3 2 3 2 1 9 7 7 7 17 27
    AA2 14 2 3 7 6 8 1 1 46 10 15 76** 46
    AA5 117 71 97** 100** 93** 90** 45 8 64 69 93** 72** 64
    AA6 9 8 99** 101** 94** 93** 56 95** 79 96** 98** 82** 72
    EE1 17 1 5 5 5 40 2 3 26 3 2 91** 56
    EE2 18 7 14 28 6 79** 10 18 15 97** 10 107** 25
    EE4 56 10 19 105** 93** 103** 91** 53 7 29 92** 33 43
    EE5 16 6 22 6 3 7 7 43 86** 9 20 25 86**
    A16 111 3 12 15 75 * 27 * * 89** * 107** *
    A27 2 16 10 9 17 * 22 * * 14 * 59 *
    D5 139 7 32 19 14 * 97** * 88** 103** * 94** 98**
    D9 6 3 1 10 5 * 15 * 56 12 * 33 93**
    D15 154 5 42 43 8 * 34 * 34 92** * 94** 39
    D24 3 1 0 63** 1 * 14 * 42 12 * 11 31
    D27 201 3 22 98** 19 * 33 * 23 21 * * 100**
    E6 4 2 91** 98** 1 * 12 12 2 * 13 16
    E7 19 0 1 2 12 * 43 * 17 23 * 93** 17
    Percentageb 100 100 82 65 82 50 88 88 87 70 62 44 73
    Controlsc 4.2 6.1 13.5 8.6 3.4 5.3 2.7 3.7 5.1 2.6 6.2 9.3 31.7
    • ↵ a A maximum of 600 trials was allowed on the 5% ethyl acetate detection, 200 trails on all other tasks. EA, Ethyl acetate.

    • ↵ b Percentage of rats tested that reached criterion performance.

    • ↵ c Mean errors. All control rats reached criterion on all tasks. A-E, Perfume, citral, 10% acetic acid, 1% acetic acid, and (+)-carvone detection tasks, respectively. D1-D4, Perfume discrimination, acetic acid versus caproic acid, acetic acid versus propionic acid, and (+)-carvone versus (−)-carvone discrimination tasks, respectively.

    • ↵* Was not tested.

    • ↵** Did not reach criterion of 85% correct responding.

Back to top

In this issue

The Journal of Neuroscience: 24 (41)
Journal of Neuroscience
Vol. 24, Issue 41
13 Oct 2004
  • Table of Contents
  • About the Cover
  • Index by author
Email

Thank you for sharing this Journal of Neuroscience article.

NOTE: We request your email address only to inform the recipient that it was you who recommended this article, and that it is not junk mail. We do not retain these email addresses.

Enter multiple addresses on separate lines or separate them with commas.
Olfaction in Olfactory Bulbectomized Rats
(Your Name) has forwarded a page to you from Journal of Neuroscience
(Your Name) thought you would be interested in this article in Journal of Neuroscience.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Print
View Full Page PDF
Citation Tools
Olfaction in Olfactory Bulbectomized Rats
Burton Slotnick, Renee Cockerham, Erin Pickett
Journal of Neuroscience 13 October 2004, 24 (41) 9195-9200; DOI: 10.1523/JNEUROSCI.1936-04.2004

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
Respond to this article
Request Permissions
Share
Olfaction in Olfactory Bulbectomized Rats
Burton Slotnick, Renee Cockerham, Erin Pickett
Journal of Neuroscience 13 October 2004, 24 (41) 9195-9200; DOI: 10.1523/JNEUROSCI.1936-04.2004
del.icio.us logo Digg logo Reddit logo Twitter logo CiteULike logo Facebook logo Google logo Mendeley logo
  • Tweet Widget
  • Facebook Like
  • Google Plus One

Jump to section

  • Article
    • Abstract
    • Introduction
    • Materials and Methods
    • Results
    • Discussion
    • Footnotes
    • References
  • Figures & Data
  • Info & Metrics
  • eLetters
  • PDF

Responses to this article

Respond to this article

Jump to comment:

No eLetters have been published for this article.

Related Articles

Cited By...

More in this TOC Section

  • Heteromodal Cortical Areas Encode Sensory-Motor Features of Word Meaning
  • Pharmacologically Counteracting a Phenotypic Difference in Cerebellar GABAA Receptor Response to Alcohol Prevents Excessive Alcohol Consumption in a High Alcohol-Consuming Rodent Genotype
  • Neuromuscular NMDA Receptors Modulate Developmental Synapse Elimination
Show more Brief Communications
  • Home
  • Alerts
  • Visit Society for Neuroscience on Facebook
  • Follow Society for Neuroscience on Twitter
  • Follow Society for Neuroscience on LinkedIn
  • Visit Society for Neuroscience on Youtube
  • Follow our RSS feeds

Content

  • Early Release
  • Current Issue
  • Issue Archive
  • Collections

Information

  • For Authors
  • For Advertisers
  • For the Media
  • For Subscribers

About

  • About the Journal
  • Editorial Board
  • Privacy Policy
  • Contact
  • Feedback
(JNeurosci logo)
(SfN logo)

Copyright © 2021 by the Society for Neuroscience.
JNeurosci Online ISSN: 1529-2401

The ideas and opinions expressed in JNeurosci do not necessarily reflect those of SfN or the JNeurosci Editorial Board. Publication of an advertisement or other product mention in JNeurosci should not be construed as an endorsement of the manufacturer’s claims. SfN does not assume any responsibility for any injury and/or damage to persons or property arising from or related to any use of any material contained in JNeurosci.