Cover picture: ~27 Intranuclear inclusionm in diameter in a spinal cord neuron of a transgenic mouse (Q71-I) expressing human mutant ataxin-3 mjd1a, the disease protein for spinocerebellar ataxia type 3 (SCA3), also known as Machadowith ataxin-3 antibody 146, counterstained with hematoxylin, and analyzed by light microscopy. For details, see the article by Goti et al. in this issue (pages 10266–10279).