Article Figures & Data
Figures
- Figure 1.
Percentage change from baseline startle (± SEM) in OVX (gray circles; n = 5), OVX estrogen-replaced (E2; black circles; n = 6), and OVX estrogen-primed, P-replaced (E2P; white circles; n = 7) female rats after ICV CRF infusion. Data were collapsed into 10 min intervals of 20 startle stimuli.
- Figure 2.
Percentage change from baseline startle (±SEM) after ICV CRF infusion in: A, OVX rats injected with oil alone (dark circles; n = 10) or progesterone (white circles; n = 10) (500 μg/100 μl oil) 4 hr before the CRF test; B, OVX rats implanted for 7 d with blank SILASTIC capsules (dark circles; n = 7) or P-filled capsules (white circles; n = 8); and C, intact virgin (dark circles; n = 6) and lactating (Xs; n = 7) female rats. Data from all three studies were collapsed into 10 min intervals of 20 startle stimuli.
- Figure 3.
Percentage change from baseline startle (±SEM) in: A, OVX rats (n = 8) tested for CRF-enhanced startle with (dark squares) and without (white squares) intraperitoneal injection of THP (10 mg/kg, by weight); and B, changes in baseline startle over a 2 hr period in OVX rats (n = 8) after injection of THP (dark squares) or vehicle (veh; white squares).
- Figure 4.
Percentage change from baseline startle (± SEM) after ICV CRF infusion in OVX rats implanted with MPA (dark squares; n = 6) or P (white squares; n = 7). Data were collapsed into 10 min intervals of 20 startle stimuli.
- Figure 5.
Percentage change from baseline startle (± SEM) after ICV CRF infusion in OVX rats (white squares; n = 22) and those implanted with SILASTIC capsules filled with MPA (dark squares; n = 6). Data were collapsed into 10 min intervals of 20 startle stimuli.
- Figure 6.
Fear-potentiated startle in: A, OVX rats implanted for 7 d with blank capsules (n = 8) or P-filled capsules (n = 9) and B, OVX rats (n = 8) tested 4 hr after either THP (10 μg/kg, by weight) injection or vehicle. Graph shows startle amplitude in the presence (light noise; white bars) and absence (noise alone; black bars) of the light cue. The difference between the two trial types (light-noise - noise alone = fear-potentiated startle; ±SEM) is depicted by gray bars.
Tables
- Table 1.
Serum Iuteinizing hormone levels in rats replaced with SILASTIC tubing containing progesterone (n = 7), medroxy-progesterone (n = 5), and untreated (n = 8)
Groups LH (in nanograms per milliliter) Untreated 6.62 ± 0.96* MPA-filled 1.42 ± 0.51 P-filled 3.15 ± 0.9 -
↵* Significantly higher than MPA- and P-implanted animals.
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