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Behavioral/Systems/Cognitive

Chronic Back Pain Is Associated with Decreased Prefrontal and Thalamic Gray Matter Density

A. Vania Apkarian, Yamaya Sosa, Sreepadma Sonty, Robert M. Levy, R. Norman Harden, Todd B. Parrish and Darren R. Gitelman
Journal of Neuroscience 17 November 2004, 24 (46) 10410-10415; https://doi.org/10.1523/JNEUROSCI.2541-04.2004
A. Vania Apkarian
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Yamaya Sosa
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Sreepadma Sonty
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Robert M. Levy
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R. Norman Harden
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Todd B. Parrish
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Darren R. Gitelman
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Article Information

DOI 
https://doi.org/10.1523/JNEUROSCI.2541-04.2004
PubMed 
15548656
Published By 
Society for Neuroscience
History 
  • Received June 25, 2004
  • Revision received October 11, 2004
  • Accepted October 12, 2004
  • First published November 17, 2004.
  • Version of record published November 17, 2004.
Copyright & Usage 
Copyright © 2004 Society for Neuroscience 0270-6474/04/2410410-06.00/0

Author Information

  1. A. Vania Apkarian1,
  2. Yamaya Sosa1,
  3. Sreepadma Sonty2,
  4. Robert M. Levy3,
  5. R. Norman Harden5,
  6. Todd B. Parrish4, and
  7. Darren R. Gitelman2,4
  1. 1Department of Physiology and Institute of Neuroscience, and Departments of 2Neurology, 3Neurosurgery, and 4Radiology, and 5Rehabilitation Institute of Chicago, Northwestern University Feinberg School of Medicine, Chicago, Illinois 60611
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Author contributions

Disclosures

    • Received June 25, 2004.
    • Revision received October 11, 2004.
    • Accepted October 12, 2004.
  • This work was supported by National Institute of Neurological Disorders and Stroke Grant NS-35115 to A.V.A. and National Institute on Aging Grant K23 AG-00940 to D.R.G. from the National Institutes of Health. We thank all patients and volunteers for participating in this study. We thank the Cognitive Brain Mapping Group, especially P. Reber, for providing MRI data of volunteers, and M. M. Mesulam, D. Small, D. Pelli, and S. A. Khan for commenting on previous versions of this manuscript.

  • Correspondence should be addressed to A. Vania Apkarian, Department of Physiology, Northwestern University Medical School, 5-120 Ward Building, 303 East Chicago Avenue, Chicago, IL 60611. E-mail: a-apkarian{at}northwestern.edu.

  • Copyright © 2004 Society for Neuroscience 0270-6474/04/2410410-06$15.00/0

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Apr 20252519766
May 202534296107
Jun 202556517
Total 20251331525389
Total2940243885514
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The Journal of Neuroscience: 24 (46)
Journal of Neuroscience
Vol. 24, Issue 46
17 Nov 2004
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Chronic Back Pain Is Associated with Decreased Prefrontal and Thalamic Gray Matter Density
A. Vania Apkarian, Yamaya Sosa, Sreepadma Sonty, Robert M. Levy, R. Norman Harden, Todd B. Parrish, Darren R. Gitelman
Journal of Neuroscience 17 November 2004, 24 (46) 10410-10415; DOI: 10.1523/JNEUROSCI.2541-04.2004

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Chronic Back Pain Is Associated with Decreased Prefrontal and Thalamic Gray Matter Density
A. Vania Apkarian, Yamaya Sosa, Sreepadma Sonty, Robert M. Levy, R. Norman Harden, Todd B. Parrish, Darren R. Gitelman
Journal of Neuroscience 17 November 2004, 24 (46) 10410-10415; DOI: 10.1523/JNEUROSCI.2541-04.2004
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