Cover picture: 5-Hydroxytryptamine (5-HT; red) and tyrosine hydroxylase (TH; green) expression in the rat cervical spinal cord 4 weeks after transection of the left dorsal roots. 5-HT and TH expression is elevated on the rhizotomized side, indicative of deafferentation-induced sprouting. An inhibitor of Rho-kinase (Y-27632) accelerates the sprouting response as well as recovery from cold hyperalgesia that develops after selective rhizotomy of the C7 and C8 roots. For details, see the article by Ramer et al. in this issue (pages 10796–10805).