Article Information
- Received September 9, 2004
- Revision received November 1, 2004
- Accepted November 1, 2004
- First published December 15, 2004.
- Version of record published December 15, 2004.
Author Information
Author contributions
Disclosures
- Received September 9, 2004.
- Revision received November 1, 2004.
- Accepted November 1, 2004.
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↵ a Throughout this paper, the six previously identified binding site regions are named by the letters A-F (Galzi and Changeux, 1994; Lester et al., 2004). Based on the structure of AChBP (Brejc et al., 2001), these regions can be defined as follows: region A, β strand 4 and loop 5; region B, β strand 7 and loop 8; region C, β strand 9, loop 10 and β strand 10; region D, β strand 2; region E, β strands 5′ and 6; region F, loop 9. When we refer to regions that are not part of the binding site, these are named by numbers based on AChBP structure.
This work was supported by National Institute of Neurological Disorders and Stroke Grant 34727 to C.C. and a Postdoctoral Fellowship from the Natural Sciences and Engineering Research Council of Canada to J.G.N.
Correspondence should be addressed to Cynthia Czajkowski, Department of Physiology, University of Wisconsin-Madison, 601 Science Drive, Madison, WI 53711. E-mail: czajkowski{at}physiology.wisc.edu.
J. G. Newell's present address: Department of Physiology, University of Toronto, Room 3318, Medical Sciences Building, 1 King's College Circle, Toronto, Ontario, Canada M5S 1A8.
R. A. McDevitt's present address: Graduate Program in Neurobiology and Behavior, University of Washington, Box 357270, Room T-471, Seattle, WA 98195.
Copyright © 2004 Society for Neuroscience 0270-6474/04/2411226-10$15.00/0
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