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Neurobiology of Disease

Inhibition of Cystine Uptake Disrupts the Growth of Primary Brain Tumors

Wook Joon Chung, Susan A. Lyons, Gina M. Nelson, Hashir Hamza, Candece L. Gladson, G. Yancey Gillespie and Harald Sontheimer
Journal of Neuroscience 3 August 2005, 25 (31) 7101-7110; DOI: https://doi.org/10.1523/JNEUROSCI.5258-04.2005
Wook Joon Chung
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Susan A. Lyons
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Gina M. Nelson
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Hashir Hamza
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Candece L. Gladson
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G. Yancey Gillespie
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Harald Sontheimer
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Article Information

DOI 
https://doi.org/10.1523/JNEUROSCI.5258-04.2005
PubMed 
16079392
Published By 
Society for Neuroscience
History 
  • Received December 23, 2004
  • Revision received June 17, 2005
  • Accepted June 17, 2005
  • First published August 3, 2005.
  • Version of record published August 3, 2005.
Copyright & Usage 
Copyright © 2005 Society for Neuroscience 0270-6474/05/257101-10.00/0

Author Information

  1. Wook Joon Chung1,
  2. Susan A. Lyons1,
  3. Gina M. Nelson1,
  4. Hashir Hamza1,
  5. Candece L. Gladson2,
  6. G. Yancey Gillespie3, and
  7. Harald Sontheimer1
  1. 1Department of Neurobiology and Civitan International Research Center, and Departments of 2Pathology and 3Neurosurgery, The University of Alabama at Birmingham, Birmingham, Alabama 35294-0021
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Author contributions

Disclosures

    • Received December 23, 2004.
    • Revision received June 17, 2005.
    • Accepted June 17, 2005.
  • This work was supported by National Institutes of Health Grants RO1-NS36692 and P50CA97247 and by a grant from the Goldhirsh Foundation. The authors do not have any competing financial interest.

  • Correspondence should be addressed to Dr. Harald Sontheimer, Civitan International Research Center 545, 1719 Sixth Avenue South, Birmingham, AL 35294-0021. E-mail: sontheimer{at}uab.edu.

  • Copyright © 2005 Society for Neuroscience 0270-6474/05/257101-10$15.00/0

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Jan 201852712
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The Journal of Neuroscience: 25 (31)
Journal of Neuroscience
Vol. 25, Issue 31
3 Aug 2005
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Inhibition of Cystine Uptake Disrupts the Growth of Primary Brain Tumors
Wook Joon Chung, Susan A. Lyons, Gina M. Nelson, Hashir Hamza, Candece L. Gladson, G. Yancey Gillespie, Harald Sontheimer
Journal of Neuroscience 3 August 2005, 25 (31) 7101-7110; DOI: 10.1523/JNEUROSCI.5258-04.2005

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Inhibition of Cystine Uptake Disrupts the Growth of Primary Brain Tumors
Wook Joon Chung, Susan A. Lyons, Gina M. Nelson, Hashir Hamza, Candece L. Gladson, G. Yancey Gillespie, Harald Sontheimer
Journal of Neuroscience 3 August 2005, 25 (31) 7101-7110; DOI: 10.1523/JNEUROSCI.5258-04.2005
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