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Cover picture: Growth cone of embryonic rat hippocampal neurons in culture stained for the synaptic vesicle markers SV2 (green) and F-actin (red). Synaptic vesicles are clustered in the central domain but are excluded from the distal region underlain by F-actin. The image shows a three-dimensional representation of the fluorescence intensities (z-axis). For details, see the article by Bonanomi et al. in this issue (pages 7299-7308).