Cover picture: Green tea has been used for medicinal purposes for thousands of years. An article in this week's Journal examines the role of its key ingredient, epigallocatechin-3-gallate (EGCG) in processing of amyloid precursor protein in a mouse model of Alzheimer's disease. See the article by Rezai-Zadeh et al. for details (pages 8807–8814). Cover photography by Julie Blair.