Neural Activity Controls the Synaptic Accumulation of α-Synuclein

This work was supported by the Hillblom Foundation (D.L.F), the University of California, San Francisco Medical Scientist Training Program grant from the National Institutes of Health (V.M.N.), the Howard Hughes Medical Institute (S.M.V.), a Society for Neuroscience Minority Fellowship (M.D.A.), the Sandler Neurogenetics Program, and the Valley Foundation (R.H.E.). We thank S. Finkbeiner and K. Svoboda for helpful discussion and W. Yan, C. Tran, J. Park, and Y. Dobryy for technical assistance.

Correspondence should be addressed to R. H. Edwards, Departments of Neurology and Physiology, University of California, San Francisco School of Medicine, 600 16th Street, San Francisco, CA 94143-2140. E-mail: edwards{at}itsa.ucsf.edu.

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