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About the Cover

March 15, 2006; Volume 26,Issue 11

Cover image

Cover legend: Although cerebral white matter injury is the major cause of neurological disability in survivors of premature birth, defining the mechanisms of fetal ischemic brain injury has been an elusive problem because of the inherent difficulties of quantifying cerebral blood flow in utero. Quantitative three-dimensional reconstructions of fetal cerebral blood flow were achieved by determining the unique location of fluorescently labeled microspheres delivered into the microcirculation. Fluorescent microspheres are shown as colored dots within a reconstructed cut-away view of the cerebral surface and were injected as four discreet populations separable by color (red, basal flow; yellow, ischemia; green and blue, 15 and 60 min of reperfusion flow, respectively). Such approaches revealed that cerebral ischemia is necessary but is not sufficient to damage the developing cerebral white matter. For details, see the article by Riddle et al. in this issue (pages 3045–3055).

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The Journal of Neuroscience: 26 (11)
Journal of Neuroscience
Vol. 26, Issue 11
15 Mar 2006
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  • An RNA-Sequencing Transcriptome and Splicing Database of Glia, Neurons, and Vascular Cells of the Cerebral Cortex
  • The Fusiform Face Area: A Module in Human Extrastriate Cortex Specialized for Face Perception
  • Dissociable Intrinsic Connectivity Networks for Salience Processing and Executive Control
  • A Transcriptome Database for Astrocytes, Neurons, and Oligodendrocytes: A New Resource for Understanding Brain Development and Function
  • The Variable Discharge of Cortical Neurons: Implications for Connectivity, Computation, and Information Coding
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