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Articles, Behavioral/Systems/Cognitive

Distinct Subtypes of Somatostatin-Containing Neocortical Interneurons Revealed in Transgenic Mice

Yunyong Ma, Hang Hu, Albert S. Berrebi, Peter H. Mathers and Ariel Agmon
Journal of Neuroscience 10 May 2006, 26 (19) 5069-5082; DOI: https://doi.org/10.1523/JNEUROSCI.0661-06.2006
Yunyong Ma
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Hang Hu
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Albert S. Berrebi
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Peter H. Mathers
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Ariel Agmon
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Table 3.

Table 3.

Summary of the phenotypic differences between X94 and X98 neurons

Phenotypic propertyX94X98
Cell body positionLayers 4 and 5BLayers 5B and 6
Layer 4 axonal arborizationsDenseNone or sparse
Layer 1 axonal arborizationsNone or sparseDense
SomatostatinAllAll
CalbindinNoneAll
Neuropeptide YNone∼40%
Input resistance<250 MΩ>300 MΩ
Time constant<20 ms>20 ms
Spike width≤0.5 ms≥0.6 ms
Fmax, initial>200 Hz<200 Hz
Fmax, steady-state>100 Hz<100 Hz
Robust stuttering∼60%∼3%
Low-threshold spikes∼2%∼40%
  • Phenotypic properties are arranged in five groups: laminar position, axonal distributions, neurochemical content, electrophysiological parameters, and firing properties. Inequalities in the electrophysiological parameters group apply to at least 90% of each population.

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The Journal of Neuroscience: 43 (5)
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