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Late Developmental Stage-Specific Role of Tryptophan Hydroxylase 1 in Brain Serotonin Levels

Kazuhiro Nakamura, Yuko Sugawara, Keiko Sawabe, Akiko Ohashi, Hiromichi Tsurui, Yan Xiu, Mareki Ohtsuji, Qing Shun Lin, Hiroyuki Nishimura, Hiroyuki Hasegawa and Sachiko Hirose
Journal of Neuroscience 11 January 2006, 26 (2) 530-534; DOI: https://doi.org/10.1523/JNEUROSCI.1835-05.2006
Kazuhiro Nakamura
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Yuko Sugawara
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Keiko Sawabe
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Akiko Ohashi
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Hiromichi Tsurui
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Yan Xiu
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Mareki Ohtsuji
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Qing Shun Lin
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Hiroyuki Nishimura
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Hiroyuki Hasegawa
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Sachiko Hirose
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Article Information

DOI 
https://doi.org/10.1523/JNEUROSCI.1835-05.2006
PubMed 
16407550
Published By 
Society for Neuroscience
History 
  • Received May 7, 2005
  • Revision received August 16, 2005
  • Accepted November 21, 2005
  • First published January 11, 2006.
  • Version of record published January 11, 2006.
Copyright & Usage 
Copyright © 2006 Society for Neuroscience 0270-6474/06/26530-05.00/0

Author Information

  1. Kazuhiro Nakamura1,
  2. Yuko Sugawara2,
  3. Keiko Sawabe2,
  4. Akiko Ohashi2,
  5. Hiromichi Tsurui1,
  6. Yan Xiu1,
  7. Mareki Ohtsuji1,
  8. Qing Shun Lin1,
  9. Hiroyuki Nishimura3,
  10. Hiroyuki Hasegawa2, and
  11. Sachiko Hirose1
  1. 1Department of Pathology, Juntendo University School of Medicine, Tokyo 113-8421, Japan, 2Department of Bioscience, Teikyo University of Science and Technology, Uenohara, Yamanashi 409-0193, Japan, and 3Department of Biomedical Engineering, Toin Human Science and Technology Center, Toin University of Yokohama, Yokohama 225-8502, Japan
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Author contributions

Disclosures

    • Received May 7, 2005.
    • Revision received August 16, 2005.
    • Accepted November 21, 2005.
  • This work was supported in part by research grants from the Ministry of Education, Science, Technology, Sports and Culture of Japan. We thank Dr. Whittemore (University of Louisville) and Dr. Stoll (Texas Tech School of Pharmacy) for the generous gifts of RN46A cells and TPH1 cDNA clone, respectively. We also thank Dr. Manabe (University of Tokyo), Dr. Aiba (Kobe University), and Dr. Bito (University of Tokyo) for critical reading.

  • Correspondence should be addressed to Kazuhiro Nakamura, Department of Pathology, Juntendo University School of Medicine, 2-1-1, Hongo, Bunkyo-ku, Tokyo 113-8421, Japan. E-mail: kaz{at}med.juntendo.ac.jp.

  • Y. Xiu's present address: Department of Immunology, Duke University Medical Center, Durham, NC 27710.

  • DOI:10.1523/JNEUROSCI.1835-05.2006

  • Copyright © 2006 Society for Neuroscience 0270-6474/06/260530-05$15.00/0

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Jan 20182185
Feb 20181128
Mar 201852515
Apr 20183138
May 201821912
Jun 20182179
Jul 201813323
Aug 20180246
Sep 20180193
Oct 201831911
Nov 201851210
Dec 20184307
Total 201828241117
Jan 20193292
Feb 20193205
Mar 201961412
Apr 20192811
May 20192268
Jun 20193203
Jul 2019596
Aug 201916508
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Nov 20196217
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Feb 20203132
Mar 20201142
May 20203195
Jun 20202167
Jul 20200122
Aug 20202134
Sep 20204207
Oct 202043924
Nov 20205319
Dec 202072512
Total 20203721780
Jan 20213225
Feb 20210105
Mar 202133216
Apr 202131114
May 20212192
Jun 20211184
Jul 202122317
Aug 20214293
Sep 20213239
Oct 202132321
Nov 202163220
Dec 20214186
Total 202134260122
Jan 20221204
Feb 20222133
Mar 20224228
Apr 20224236
May 202211412
Jun 20222167
Jul 20223281
Aug 20222193
Sep 202242819
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Total 20222724079
Jan 202323712
Feb 202322911
Mar 20235375
Total 2023910328
Total1961328507
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The Journal of Neuroscience: 26 (2)
Journal of Neuroscience
Vol. 26, Issue 2
11 Jan 2006
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Late Developmental Stage-Specific Role of Tryptophan Hydroxylase 1 in Brain Serotonin Levels
Kazuhiro Nakamura, Yuko Sugawara, Keiko Sawabe, Akiko Ohashi, Hiromichi Tsurui, Yan Xiu, Mareki Ohtsuji, Qing Shun Lin, Hiroyuki Nishimura, Hiroyuki Hasegawa, Sachiko Hirose
Journal of Neuroscience 11 January 2006, 26 (2) 530-534; DOI: 10.1523/JNEUROSCI.1835-05.2006

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Late Developmental Stage-Specific Role of Tryptophan Hydroxylase 1 in Brain Serotonin Levels
Kazuhiro Nakamura, Yuko Sugawara, Keiko Sawabe, Akiko Ohashi, Hiromichi Tsurui, Yan Xiu, Mareki Ohtsuji, Qing Shun Lin, Hiroyuki Nishimura, Hiroyuki Hasegawa, Sachiko Hirose
Journal of Neuroscience 11 January 2006, 26 (2) 530-534; DOI: 10.1523/JNEUROSCI.1835-05.2006
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