Skip to main content

Main menu

  • HOME
  • CONTENT
    • Early Release
    • Featured
    • Current Issue
    • Issue Archive
    • Collections
    • Podcast
  • ALERTS
  • FOR AUTHORS
    • Information for Authors
    • Fees
    • Journal Clubs
    • eLetters
    • Submit
  • EDITORIAL BOARD
  • ABOUT
    • Overview
    • Advertise
    • For the Media
    • Rights and Permissions
    • Privacy Policy
    • Feedback
  • SUBSCRIBE

User menu

  • Log in
  • My Cart

Search

  • Advanced search
Journal of Neuroscience
  • Log in
  • My Cart
Journal of Neuroscience

Advanced Search

Submit a Manuscript
  • HOME
  • CONTENT
    • Early Release
    • Featured
    • Current Issue
    • Issue Archive
    • Collections
    • Podcast
  • ALERTS
  • FOR AUTHORS
    • Information for Authors
    • Fees
    • Journal Clubs
    • eLetters
    • Submit
  • EDITORIAL BOARD
  • ABOUT
    • Overview
    • Advertise
    • For the Media
    • Rights and Permissions
    • Privacy Policy
    • Feedback
  • SUBSCRIBE
PreviousNext
Articles, Development/Plasticity/Repair

Temporal and Spatial Dynamics of Brain Structure Changes during Extensive Learning

Bogdan Draganski, Christian Gaser, Gerd Kempermann, H. Georg Kuhn, Jürgen Winkler, Christian Büchel and Arne May
Journal of Neuroscience 7 June 2006, 26 (23) 6314-6317; DOI: https://doi.org/10.1523/JNEUROSCI.4628-05.2006
Bogdan Draganski
1Department of Neurology, University of Regensburg, 93053 Regensburg, Germany 2Department of Psychiatry, University of Jena, 07743 Jena, Germany, 3Max-Delbrück Center for Molecular Medicine, 13092 Berlin, Germany, 4Institute for Neuroscience and Physiology, Gothenburg University, SE 405 30 Gothenburg, Sweden, and 5Department of Systems Neuroscience, University of Hamburg, 20246 Hamburg, Germany
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Christian Gaser
1Department of Neurology, University of Regensburg, 93053 Regensburg, Germany 2Department of Psychiatry, University of Jena, 07743 Jena, Germany, 3Max-Delbrück Center for Molecular Medicine, 13092 Berlin, Germany, 4Institute for Neuroscience and Physiology, Gothenburg University, SE 405 30 Gothenburg, Sweden, and 5Department of Systems Neuroscience, University of Hamburg, 20246 Hamburg, Germany
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Gerd Kempermann
1Department of Neurology, University of Regensburg, 93053 Regensburg, Germany 2Department of Psychiatry, University of Jena, 07743 Jena, Germany, 3Max-Delbrück Center for Molecular Medicine, 13092 Berlin, Germany, 4Institute for Neuroscience and Physiology, Gothenburg University, SE 405 30 Gothenburg, Sweden, and 5Department of Systems Neuroscience, University of Hamburg, 20246 Hamburg, Germany
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
H. Georg Kuhn
1Department of Neurology, University of Regensburg, 93053 Regensburg, Germany 2Department of Psychiatry, University of Jena, 07743 Jena, Germany, 3Max-Delbrück Center for Molecular Medicine, 13092 Berlin, Germany, 4Institute for Neuroscience and Physiology, Gothenburg University, SE 405 30 Gothenburg, Sweden, and 5Department of Systems Neuroscience, University of Hamburg, 20246 Hamburg, Germany
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Jürgen Winkler
1Department of Neurology, University of Regensburg, 93053 Regensburg, Germany 2Department of Psychiatry, University of Jena, 07743 Jena, Germany, 3Max-Delbrück Center for Molecular Medicine, 13092 Berlin, Germany, 4Institute for Neuroscience and Physiology, Gothenburg University, SE 405 30 Gothenburg, Sweden, and 5Department of Systems Neuroscience, University of Hamburg, 20246 Hamburg, Germany
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Christian Büchel
1Department of Neurology, University of Regensburg, 93053 Regensburg, Germany 2Department of Psychiatry, University of Jena, 07743 Jena, Germany, 3Max-Delbrück Center for Molecular Medicine, 13092 Berlin, Germany, 4Institute for Neuroscience and Physiology, Gothenburg University, SE 405 30 Gothenburg, Sweden, and 5Department of Systems Neuroscience, University of Hamburg, 20246 Hamburg, Germany
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Arne May
1Department of Neurology, University of Regensburg, 93053 Regensburg, Germany 2Department of Psychiatry, University of Jena, 07743 Jena, Germany, 3Max-Delbrück Center for Molecular Medicine, 13092 Berlin, Germany, 4Institute for Neuroscience and Physiology, Gothenburg University, SE 405 30 Gothenburg, Sweden, and 5Department of Systems Neuroscience, University of Hamburg, 20246 Hamburg, Germany
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • Article
  • Figures & Data
  • Info & Metrics
  • eLetters
  • PDF
Loading

Article Figures & Data

Figures

  • Figure 1.
    • Download figure
    • Open in new tab
    • Download powerpoint
    Figure 1.

    Gray matter increase related to learning. Statistical parametric maps demonstrating the structural difference in gray matter during the learning period in medical students. The left side of the picture is the left side of the brain (L, left; R, right). A, Significant gray matter increase between the first two time points (p < 0.05, corrected for multiple comparisons using FWE) in posterior parietal cortex is superimposed on the cortical surface of a representative single subject. B, Significant gray matter increase between the first, second, and third time points in the hippocampus. The image is superimposed (p < 0.001 uncorrected) onto two selected slices of a representative single subject. The right hippocampus is significant at p < 0.05 (FWE corrected), and the left hippocampus is significant after application of a small volume correction using the hippocampal region as defined in the WFU PickAtlas (p < 0.05, FWE corrected). C, Plots of percentage of signal change (black line) and 90% confidence interval (red line) averaged over the cluster of the right posterior parietal cortex (C1) and left hippocampus (C2) over the three time points. The gray matter increase in the parietal cortex had not changed significantly between the second and third scans during the semester break 3 months later. The posterior hippocampus showed an initial increase in gray matter during the learning period, which was even more pronounced in the third scan after the learning period.

  • Figure 2.
    • Download figure
    • Open in new tab
    • Download powerpoint
    Figure 2.

    Gray matter increases and decreases displayed as maximum intensity projection. Gray matter increases (red) and decreases (green) are simultaneously shown in a so-called maximum intensity projection, with threshold at p < 0.05 (corrected for multiple comparisons using FWE).

Back to top

In this issue

The Journal of Neuroscience: 26 (23)
Journal of Neuroscience
Vol. 26, Issue 23
7 Jun 2006
  • Table of Contents
  • About the Cover
  • Index by author
Email

Thank you for sharing this Journal of Neuroscience article.

NOTE: We request your email address only to inform the recipient that it was you who recommended this article, and that it is not junk mail. We do not retain these email addresses.

Enter multiple addresses on separate lines or separate them with commas.
Temporal and Spatial Dynamics of Brain Structure Changes during Extensive Learning
(Your Name) has forwarded a page to you from Journal of Neuroscience
(Your Name) thought you would be interested in this article in Journal of Neuroscience.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Print
View Full Page PDF
Citation Tools
Temporal and Spatial Dynamics of Brain Structure Changes during Extensive Learning
Bogdan Draganski, Christian Gaser, Gerd Kempermann, H. Georg Kuhn, Jürgen Winkler, Christian Büchel, Arne May
Journal of Neuroscience 7 June 2006, 26 (23) 6314-6317; DOI: 10.1523/JNEUROSCI.4628-05.2006

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
Respond to this article
Request Permissions
Share
Temporal and Spatial Dynamics of Brain Structure Changes during Extensive Learning
Bogdan Draganski, Christian Gaser, Gerd Kempermann, H. Georg Kuhn, Jürgen Winkler, Christian Büchel, Arne May
Journal of Neuroscience 7 June 2006, 26 (23) 6314-6317; DOI: 10.1523/JNEUROSCI.4628-05.2006
del.icio.us logo Digg logo Reddit logo Twitter logo CiteULike logo Facebook logo Google logo Mendeley logo
  • Tweet Widget
  • Facebook Like
  • Google Plus One

Jump to section

  • Article
    • Abstract
    • Introduction
    • Materials and Methods
    • Results
    • Discussion
    • Footnotes
    • References
  • Figures & Data
  • Info & Metrics
  • eLetters
  • PDF

Keywords

  • brain
  • plasticity
  • posterior parietal cortex
  • hippocampus
  • memory
  • learning
  • voxel-based morphometry

Responses to this article

Respond to this article

Jump to comment:

No eLetters have been published for this article.

Related Articles

Cited By...

More in this TOC Section

Articles

  • Choice Behavior Guided by Learned, But Not Innate, Taste Aversion Recruits the Orbitofrontal Cortex
  • Maturation of Spontaneous Firing Properties after Hearing Onset in Rat Auditory Nerve Fibers: Spontaneous Rates, Refractoriness, and Interfiber Correlations
  • Insulin Treatment Prevents Neuroinflammation and Neuronal Injury with Restored Neurobehavioral Function in Models of HIV/AIDS Neurodegeneration
Show more Articles

Development/Plasticity/Repair

  • Post-synaptic NMDA Receptor Expression Is Required for Visual Corticocollicular Projection Refinement in the Mouse Superior Colliculus
  • Spatiotemporal Developmental Gradient of Thalamic Morphology, Microstructure, and Connectivity fromthe Third Trimester to Early Infancy
  • Loss of motor cortical inputs to the red nucleus after central nervous system disorders in non-human primates
Show more Development/Plasticity/Repair
  • Home
  • Alerts
  • Visit Society for Neuroscience on Facebook
  • Follow Society for Neuroscience on Twitter
  • Follow Society for Neuroscience on LinkedIn
  • Visit Society for Neuroscience on Youtube
  • Follow our RSS feeds

Content

  • Early Release
  • Current Issue
  • Issue Archive
  • Collections

Information

  • For Authors
  • For Advertisers
  • For the Media
  • For Subscribers

About

  • About the Journal
  • Editorial Board
  • Privacy Policy
  • Contact
(JNeurosci logo)
(SfN logo)

Copyright © 2023 by the Society for Neuroscience.
JNeurosci Online ISSN: 1529-2401

The ideas and opinions expressed in JNeurosci do not necessarily reflect those of SfN or the JNeurosci Editorial Board. Publication of an advertisement or other product mention in JNeurosci should not be construed as an endorsement of the manufacturer’s claims. SfN does not assume any responsibility for any injury and/or damage to persons or property arising from or related to any use of any material contained in JNeurosci.