Article Information
PubMed
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History
- Received March 20, 2006
- Revision received July 24, 2006
- Accepted August 24, 2006
- First published October 4, 2006.
- Version of record published October 4, 2006.
Copyright & Usage
Copyright © 2006 Society for Neuroscience 0270-6474/06/2610129-13$15.00/0
Author Information
- Holly Oakley1,
- Sarah L. Cole1,
- Sreemathi Logan1,
- Erika Maus1,
- Pei Shao1,
- Jeffery Craft1,
- Angela Guillozet-Bongaarts1,
- Masuo Ohno2,
- John Disterhoft2,
- Linda Van Eldik1,
- Robert Berry1, and
- Robert Vassar1
- Departments of 1Cell and Molecular Biology and
- 2Physiology, The Feinberg School of Medicine, Northwestern University, Chicago, Illinois 60611
- Correspondence should be addressed to Dr. Robert Vassar, Department of Cell and Molecular Biology, The Feinberg School of Medicine, Northwestern University, 303 East Chicago Avenue, Chicago, IL 60611. r-vassar{at}northwestern.edu
Author contributions
Disclosures
- Received March 20, 2006.
- Revision received July 24, 2006.
- Accepted August 24, 2006.
-
This work was supported by National Institute on Aging Grants P01 AG021184 (Project 1, L.V.E.; Project 4, R.V.; Histology Core, R.B.) and R01 AG022560 (R.V.) We are indebted to Lynn Doglio and her staff at the Northwestern Transgenic and Targeted Mutagenesis Laboratory for transgene microinjection and production of founder transgenic mice. We also thank the following individuals for their valuable input on this project: Fred Van Leuven for the Thy1 transgene cassette vector, Leong Chew for assistance with confocal imaging, Gopal Thinakaran for the PS1NT antibody, Dennis Selkoe for the R1282 antibody, and Marsel Mesulam, Richard Miller, Gunnar Gouras, Frank Laferla, and Sam Sisodia for thoughtful comments on this manuscript.
- Correspondence should be addressed to Dr. Robert Vassar, Department of Cell and Molecular Biology, The Feinberg School of Medicine, Northwestern University, 303 East Chicago Avenue, Chicago, IL 60611. r-vassar{at}northwestern.edu