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Articles, Cellular/Molecular

Perturbed Interactions of Mutant Proteolipid Protein/DM20 with Cholesterol and Lipid Rafts in Oligodendroglia: Implications for Dysmyelination in Spastic Paraplegia

Eva-Maria Krämer-Albers, Katja Gehrig-Burger, Christoph Thiele, Jacqueline Trotter and Klaus-Armin Nave
Journal of Neuroscience 8 November 2006, 26 (45) 11743-11752; https://doi.org/10.1523/JNEUROSCI.3581-06.2006
Eva-Maria Krämer-Albers
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Katja Gehrig-Burger
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Christoph Thiele
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Jacqueline Trotter
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Klaus-Armin Nave
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Article Information

DOI 
https://doi.org/10.1523/JNEUROSCI.3581-06.2006
PubMed 
17093095
Published By 
Society for Neuroscience
History 
  • Received April 12, 2006
  • Revision received September 19, 2006
  • Accepted September 19, 2006
  • First published November 8, 2006.
  • Version of record published November 8, 2006.
Copyright & Usage 
Copyright © 2006 Society for Neuroscience 0270-6474/06/2611743-10$15.00/0

Author Information

  1. Eva-Maria Krämer-Albers1,3,
  2. Katja Gehrig-Burger2,
  3. Christoph Thiele4,
  4. Jacqueline Trotter1, and
  5. Klaus-Armin Nave3,5
  1. 1Department of Biology, Unit of Molecular Cell Biology, and
  2. 2Institute of Biochemistry, University of Mainz, 55099 Mainz, Germany,
  3. 3Department of Neurogenetics, Max Planck Institute of Experimental Medicine, 37075 Göttingen, Germany,
  4. 4Max Planck Institute of Molecular Cell Biology and Genetics, 01307 Dresden, Germany, and
  5. 5Hertie Institute of Multiple Sclerosis Research, 37075 Göttingen, Germany
  1. Correspondence should be addressed to Eva-Maria Krämer-Albers, Department of Biology, Unit of Molecular Cell Biology, Johannes Gutenberg University Mainz, Bentzelweg 3, 55128 Mainz, Germany. emkraemer{at}uni-mainz.de
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Author contributions

Disclosures

    • Received April 12, 2006.
    • Revision received September 19, 2006.
    • Accepted September 19, 2006.
  • This work was supported by Deutsche Forschungsgemeinschaft Grant SFB523 (K.-A.N.) and a grant from the European Leukodystrophy Association (E.-M.K.-A.). We thank Ulrike Stapf and Lilja Niedens for excellent technical assistance, Christine Winterstein for providing images, and Gesine Saher for critical comments on this manuscript.

  • Correspondence should be addressed to Eva-Maria Krämer-Albers, Department of Biology, Unit of Molecular Cell Biology, Johannes Gutenberg University Mainz, Bentzelweg 3, 55128 Mainz, Germany. emkraemer{at}uni-mainz.de

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Total4173175879
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The Journal of Neuroscience: 26 (45)
Journal of Neuroscience
Vol. 26, Issue 45
8 Nov 2006
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Perturbed Interactions of Mutant Proteolipid Protein/DM20 with Cholesterol and Lipid Rafts in Oligodendroglia: Implications for Dysmyelination in Spastic Paraplegia
Eva-Maria Krämer-Albers, Katja Gehrig-Burger, Christoph Thiele, Jacqueline Trotter, Klaus-Armin Nave
Journal of Neuroscience 8 November 2006, 26 (45) 11743-11752; DOI: 10.1523/JNEUROSCI.3581-06.2006

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Perturbed Interactions of Mutant Proteolipid Protein/DM20 with Cholesterol and Lipid Rafts in Oligodendroglia: Implications for Dysmyelination in Spastic Paraplegia
Eva-Maria Krämer-Albers, Katja Gehrig-Burger, Christoph Thiele, Jacqueline Trotter, Klaus-Armin Nave
Journal of Neuroscience 8 November 2006, 26 (45) 11743-11752; DOI: 10.1523/JNEUROSCI.3581-06.2006
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