Figure 1.
The role of CE in the acquisition of auditory fear conditioning. a, Procedural outline and mean ± SE percentage freezing during CS presentation averaged across all tone trials. Freezing scores after functional inactivation of either CE or LA were significantly decreased from control groups (*p < 0.05). The average freezing after functional inactivation of CE was also significantly different from that of LA (p < 0.05). b, Mean ± SE percentage freezing per group during each tone trial. c, Procedural outline for functional inactivation of CE during expression and mean ± SE percentage freezing to CS presentation averaged across all tone trials during testing and 24 h later, drug free. Although muscimol significantly decreased freezing (*p < 0.05), muscimol-treated animals did not differ from controls when retested drug free. d, Cannula tip placements for all animals included in analysis (drawings adapted from Paxinos and Watson, 1997). Numbers on the left refer to posterior to bregma in millimeters. B, Basal nucleus.