Cover legend: The image shows immunoreactivity for neurotrophin receptor P75NTR (green) at mouse neuromuscular junctions labeled with α-bungarotoxin (red). Hoechst staining (blue) shows the multinucleation of soleus muscle fibers. P75NTR is expressed in motorneuron terminals and terminal Schwann cells at denervated neuromuscular junctions. Neuroprotection with the histone deacetylase inhibitor sodium valproate did not prevent P75NTR expression in a mouse model of amyotrophic lateral sclerosis, indicating that neuroprotection was not sufficient to prevent neuromuscular damage. For more information, see the article by Rouaux et al. in this issue (pages 5535–5545).