Figure 2.
A–D, Effects of CUMS on excitotoxic brain lesions induced by ibotenate (A–D), NMDA (E, F), or S-bromowillardiine (G, H) in C57BL/6 mice. Excitotoxins were injected at P5, and pups were killed at P10. Bars represent mean sagittal diameter (A, C, E, G) or mean volume (B, D, F, H) of the lesions ± SEM. Asterisks indicate statistically significant difference from control males (A–D) or controls (E–H). *p < 0.05, **p < 0.01, ***p < 0.001 in three-way ANOVA with contrasts (A–G) or in Student's t test (E–H). Ctrl, Control.