Article Information
- Received February 27, 2007
- Revision received June 1, 2007
- Accepted July 5, 2007
- First published August 22, 2007.
- Version of record published August 22, 2007.
Author Information
- Karolina Wosik1,*,
- Romain Cayrol1,*,
- Aurore Dodelet-Devillers1,
- France Berthelet2,
- Monique Bernard1,
- Robert Moumdjian3,
- Alain Bouthillier3,
- Timothy L. Reudelhuber5, and
- Alexandre Prat1,4,6
- 1Neuroimmunology Research Laboratory, Center for Study of Brain Diseases,
- 2Department of Neuropathology,
- 3Department of Neurosurgery,
- 4Department of Neurology,
- 5Laboratory of Molecular Biochemistry of Hypertension, Clinical Research Institute of Montreal, and
- 6Multiple Sclerosis Clinic, Department of Neurology, Centre Hospitalier de l'Université de Montréal-Notre Dame Hospital, University of Montreal, Montréal, Quebec, Canada H2L 4M1
- Correspondence should be addressed to Dr. Alexandre Prat, Multiple Sclerosis Clinic and Neuroimmunology Research Laboratory, Centre Hospitalier de l'Université de Montréal-Notre Dame Hospital, 1560 Sherbrooke Street East, Montréal, Quebec, Canada H2L 4M1. a.prat{at}umontreal.ca
Author contributions
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↵*K.W. and R.C. contributed equally to this work.
Disclosures
- Received February 27, 2007.
- Revision received June 1, 2007.
- Accepted July 5, 2007.
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This work was supported by grants from the Canadian Institute of Health Research (CIHR) (INO-Neuroscience Mental Health and Addiction and MOP81088), the Multiple Sclerosis Society of Canada (MSSC), and the Canadian Foundation for Innovation. A.P. holds the Donald Paty Career Development Award of the MSSC and is a Research Scholar (Junior 1) from the Fonds de Recherche en Santé du Québec. K.W. holds a fellowship from the MSSC. A.D.-D. and R.C. hold a CIHR-sponsored neuroinflammation training grant studentship. We thank Stephanie Jack for her work in setting up the MS brain bank, Dr. T. Vincent for his work with BBB-ECs/astrocyte cocultures, and Dr. Chan for the generous gift of the AT1 antagonist as well as Dr. Nathalie Arbour, Hania Kébir, and Igal Ifergan for critical reading of this manuscript.
- Correspondence should be addressed to Dr. Alexandre Prat, Multiple Sclerosis Clinic and Neuroimmunology Research Laboratory, Centre Hospitalier de l'Université de Montréal-Notre Dame Hospital, 1560 Sherbrooke Street East, Montréal, Quebec, Canada H2L 4M1. a.prat{at}umontreal.ca
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