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Articles, Cellular/Molecular

Progressive Loss of Dopaminergic Neurons in the Ventral Midbrain of Adult Mice Heterozygote for Engrailed1

Laure Sonnier, Gwenaëlle Le Pen, Andreas Hartmann, Jean-Charles Bizot, Fabrice Trovero, Marie-Odile Krebs and Alain Prochiantz
Journal of Neuroscience 31 January 2007, 27 (5) 1063-1071; DOI: https://doi.org/10.1523/JNEUROSCI.4583-06.2007
Laure Sonnier
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Gwenaëlle Le Pen
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Andreas Hartmann
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Jean-Charles Bizot
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Fabrice Trovero
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Marie-Odile Krebs
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Alain Prochiantz
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Article Information

DOI 
https://doi.org/10.1523/JNEUROSCI.4583-06.2007
PubMed 
17267560
Published By 
Society for Neuroscience
History 
  • Received October 23, 2006
  • Revision received December 20, 2006
  • Accepted December 20, 2006
  • First published January 31, 2007.
  • Version of record published January 31, 2007.
Copyright & Usage 
Copyright © 2007 Society for Neuroscience 0270-6474/07/271063-09$15.00/0

Author Information

  1. Laure Sonnier1,*,
  2. Gwenaëlle Le Pen2,*,
  3. Andreas Hartmann3,
  4. Jean-Charles Bizot4,
  5. Fabrice Trovero4,
  6. Marie-Odile Krebs2, and
  7. Alain Prochiantz1
  1. 1Centre National de la Recherche Scientifique, Unité Mixte de Recherche 8542, Development and Evolution of the Nervous System, Group Development and Neuropharmacology, Ecole Normale Supérieure, 75230 Paris Cedex 05, France,
  2. 2Institut National de la Santé et de la Recherche Médicale, Unit 796, Pathophysiology of Psychiatric Disorders, University Paris Descartes, Faculty of Medicine Paris Descartes, Sainte-Anne Hospital, Paris F-75014, France,
  3. 3Institut National de la Santé et de la Recherche Médicale, Unit 679, Neurology and Experimental Therapeutics, Hospital of Pitié-Salpêtrière and University Pierre and Marie Curie, Faculty of Medicine, Paris 75013, France, and
  4. 4Keyobs, Centre d'Innovation, 45100 Orléans Cedex 2, France
  1. Correspondence should be addressed to Alain Prochiantz, Centre National de la Recherche Scientifique, Unité Mixte de Recherche 8542, Development and Evolution of the Nervous System, Group Development and Neuropharmacology, Ecole Normale Supérieure, 46 Rue d'Ulm, 75230 Paris Cedex 05, France. Alain.Prochiantz{at}ens.fr
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Author contributions

  1. ↵*L.S. and G.L.P. have contributed equally to this work.

Disclosures

    • Received October 23, 2006.
    • Revision received December 20, 2006.
    • Accepted December 20, 2006.
  • This work was supported by Centre National de la Recherche Scientifique (CNRS), Institut National de la Recherche Médicale, and Ecole Normale Supérieure. Specific support also was obtained from the Association Française contre les Myopathies (Grant 2006-12208), Fondation de France (Grant 2004-013352), and Michael J. Fox Foundation (Fast Track 2004 Award). We thank Dr. Marie-Françoise Chesselet for her careful reading of this manuscript and valuable advice. Our thanks also go to Dr. Armen Sagatelyan and Professor Michel Volovitch for their help in designing and analyzing some experiments. We are grateful to Stéphane Dupas (CNRS; UMR8542), Sabrina David, Alexandra Herpin, and Stéphanie Pothion (Keyobs) for excellent technical assistance.

  • Correspondence should be addressed to Alain Prochiantz, Centre National de la Recherche Scientifique, Unité Mixte de Recherche 8542, Development and Evolution of the Nervous System, Group Development and Neuropharmacology, Ecole Normale Supérieure, 46 Rue d'Ulm, 75230 Paris Cedex 05, France. Alain.Prochiantz{at}ens.fr

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Jan 201811205
Feb 2018201611
Mar 20185107
Apr 20183228
May 20180187
Jun 20181158
Jul 20184187
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Jan 20192229
Feb 201951513
Mar 20192238
Apr 20192175
May 2019327204
Jun 201964288
Jul 201918167
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Feb 20201233
Mar 20202195
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Jun 20202176
Jul 20201134
Aug 20204148
Sep 202061126
Oct 20202246
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Total 20205733798
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Feb 20210165
Mar 202193620
Apr 20215203
May 2021112814
Jun 20216209
Jul 202112011
Aug 20213185
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Oct 202152627
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Total 202159285155
Jan 20226295
Feb 20223213
Mar 2022142913
Apr 202212826
May 202273424
Jun 20222185
Jul 20224256
Aug 20226207
Sep 20220138
Oct 202246311
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Total 202250294116
Jan 202323014
Feb 20236168
Mar 202352812
Total 2023137434
Total6831505564
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The Journal of Neuroscience: 27 (5)
Journal of Neuroscience
Vol. 27, Issue 5
31 Jan 2007
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Progressive Loss of Dopaminergic Neurons in the Ventral Midbrain of Adult Mice Heterozygote for Engrailed1
Laure Sonnier, Gwenaëlle Le Pen, Andreas Hartmann, Jean-Charles Bizot, Fabrice Trovero, Marie-Odile Krebs, Alain Prochiantz
Journal of Neuroscience 31 January 2007, 27 (5) 1063-1071; DOI: 10.1523/JNEUROSCI.4583-06.2007

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Progressive Loss of Dopaminergic Neurons in the Ventral Midbrain of Adult Mice Heterozygote for Engrailed1
Laure Sonnier, Gwenaëlle Le Pen, Andreas Hartmann, Jean-Charles Bizot, Fabrice Trovero, Marie-Odile Krebs, Alain Prochiantz
Journal of Neuroscience 31 January 2007, 27 (5) 1063-1071; DOI: 10.1523/JNEUROSCI.4583-06.2007
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