Article Information
- Received September 17, 2007
- Revision received November 8, 2007
- Accepted November 8, 2007
- First published December 19, 2007.
- Version of record published December 19, 2007.
Author Information
- Daniel K. Mulkey*,
- Edmund M. Talley*,
- Ruth L. Stornetta,
- Audra R. Siegel,
- Gavin H. West,
- Xiangdong Chen,
- Neil Sen,
- Akshitkumar M. Mistry,
- Patrice G. Guyenet, and
- Douglas A. Bayliss
- Correspondence should be addressed to Douglas A. Bayliss, Department of Pharmacology, University of Virginia, Charlottesville, VA 22908-0735. dab3y{at}virginia.edu
Author contributions
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↵*D.K.M. and E.M.T. contributed equally to this work.
Disclosures
- Received September 17, 2007.
- Revision received November 8, 2007.
- Accepted November 8, 2007.
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This work was supported by National Institutes of Health Grants F32 HL80890 (D.K.M.), HL74011 (P.G.G.), and NS33583 (D.A.B.), by the Summer Research Internship Program at the University of Virginia (A.R.S.), and by a Parker B. Francis Fellowship from the Francis Families Foundation (E.M.T.). We thank the following for reagents and/or conceptual support: Drs. Timothy Bender, Scott Zeitlin, Sonia Pearson-White, and Richard Palmiter. We are grateful to Taylor Herbert, Rowena Crittenden, and Maggie Ober for technical support in making targeting constructs, performing ES cell culture, and blastocyst injections; and to Jules Manger, Shaofang Shu, Jamie Keller-Robinson, Katherine Hopper, and Steve Rekant for help with basic characterization of the knock-outs.
- Correspondence should be addressed to Douglas A. Bayliss, Department of Pharmacology, University of Virginia, Charlottesville, VA 22908-0735. dab3y{at}virginia.edu
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