Article Information
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History
- Received November 21, 2007
- Revision received February 13, 2008
- Accepted February 13, 2008
- Published in print March 26, 2008.
Copyright & Usage
Copyright © 2008 Society for Neuroscience 0270-6474/08/283384-08$15.00/0
Author Information
- Lizhen Wang1,
- Chengsong Xie1,
- Elisa Greggio2,
- Loukia Parisiadou1,
- Hoon Shim1,
- Lixin Sun1,
- Jayanth Chandran1,
- Xian Lin1,
- Chen Lai1,
- Wan-Jou Yang1,
- Darren J. Moore3,4,
- Ted M. Dawson3,4,5,
- Valina L. Dawson3,4,5,
- Gabriela Chiosis6,
- Mark R. Cookson2, and
- Huaibin Cai1
- Units of 1Transgenesis and
- 2Cell Biology and Gene Expression, Laboratory of Neurogenetics, National Institute on Aging, Bethesda, Maryland 20892,
- 3Institute for Cell Engineering,
- Departments of 4Neurology and
- 5Neuroscience, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21025, and
- 6Program in Molecular Pharmacology and Chemistry, Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, New York 10021
- Correspondence should be addressed to Huaibin Cai, Unit of Transgenesis, Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Building 35, Room 1A116, MSC 3707, 35 Convent Drive, Bethesda, MD 20892-3707. caih{at}mail.nih.gov
Author contributions
Disclosures
- Received November 21, 2007.
- Revision received February 13, 2008.
- Accepted February 13, 2008.
-
This work was supported by the intramural research programs of the National Institute on Aging and the National Human Genome Research Institute and in part by the National Institute of Aging Grant 1R21AG028811 (G.C.). We thank Amy Chen of the Mouse Embryonic Stem Cell and Transgenic Core Facility, National Human Genome Research Institute, National Institutes of Health for pronuclear injection, and Dr. David Borchelt (University or Florida, Gainesville, FL) for providing the Prp-tet gene expression vector.
-
The authors declare no competing financial interests.
- Correspondence should be addressed to Huaibin Cai, Unit of Transgenesis, Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Building 35, Room 1A116, MSC 3707, 35 Convent Drive, Bethesda, MD 20892-3707. caih{at}mail.nih.gov
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