Figure 5.
Place-cell activity showed a dynamic change on new trajectories. A, Rate maps of seven example place cells (a–g), each from a different session, during baseline laps on the two alternating trajectories (LR, RL) and during consecutive blocks of 3 laps on the new trajectories (LL or RR). Only the central track and its surrounding segments are shown. E and T are the central track entrance and exit, respectively. Each row represents a cell. Color codes firing rate with maps within a row sharing the same peak rate (number in hertz). B, Central track mean rates and field COMs of all the cells during the first (early) and last (late) two blocks of laps on the new trajectories. Each line represents a cell. Blue lines, Cells showing a significant rate change (correlation between rates or COMs and lap numbers with p < 0.05) on the new trajectories that became more similar to same-past trajectories. Red lines, Cells showing a significant change toward different-past trajectories. Gray lines, Cells without a significant change. C, Central track mean rate changes of all the cells on new trajectories, compared with the changes on same-past and different-past familiar trajectories before the first actual laps on new trajectories. Each dot represents the rate change of a place cell on a new trajectory (rate change 1: rate difference between the first and last two blocks of laps on the new trajectory) and on a familiar trajectory (rate change 2: rate difference between the baseline laps and the laps after the switching but before the actual first laps on new trajectories). Solid lines, Linear regressions.
