Article Figures & Data
Figures
- Figure 1.
Schematic drawing of the modified Simon task. Each trial started with the presentation of a congruency cue. In the choice condition, participants indicated their preference for receiving a congruent or incongruent target stimulus by selecting either C (congruent) or I (incongruent) with the middle finger or the index finger of the left hand. In the no-choice condition (data not shown here), the congruency cue either conveyed C or I information. The target matched the cue in 70% of the trials (valid trials; top), whereas in 30% of the trials, target congruence did not match the cue (invalid trials; bottom). The target stimuli consisted of green and red circles that were associated with a left and right button press, respectively, with the index or middle fingers of the right hand. In congruent trials, responses were spatially compatible with the location of the target stimulus (e.g., left green circle leads to an index finger response), whereas in incongruent targets, participants' responses were spatially incompatible with the location of the stimulus (e.g., left red circle leads to a middle finger response).
- Figure 2.
Selective response inhibition covariate analysis with individual parameters derived from 14 participants for each segment of the delta plot (depicted in red). Top, The delta slopes separated in fast and slow segments for invalidly cued trials. Middle, Pearson correlations (two-tailed) between the percentage of signal changes (y-axis) derived from the rIFC and the demeaned delta slopes (x-axis) for each segment of the delta plot. Bottom, The averaged activation across 14 participants rendered onto a template brain (z > 2.3, p < 0.05, whole-brain corrected) of the covariance analysis with the two segments of the delta plot. The only significant prefrontal activation is obtained for the slowest segment of the delta plot in the rIFC (Brodmann's area 44; x = 50, y = 26, z = 8). Coordinates are given in MNI space.
- Figure 3.
Function and structure of the rIFC. BOLD data were transformed on the basis of a nonlinear transformation from MNI to tract-based space (the transformation used in DTI analysis) to allow comparison of DTI (red) and fMRI (blue) results (see also Materials and Methods). A, Axial view. Inferior FOF is displayed in green and derived from the Johns Hopkins University White-Matter Tractography Atlas implemented in FSL (FMRIB's Software Library, www.fmrib.ox.ac.uk/fsl; Version 4.0). B, Pearson correlation (one-tailed) between FA values derived from the anterior part of the FOF and demeaned slope values derived from the delta plot of the slowest segment for invalidly cued trials. C, Pearson correlation (two-tailed) between FA values from the anterior part of the inferior FOF and percentage BOLD signal change derived from the rIFC.
