Article Information
- Received April 27, 2008
- Revision received July 20, 2008
- Accepted July 30, 2008
- First published October 8, 2008.
- Version of record published October 8, 2008.
Author Information
- Carrie K. Jones 1 , 5 ,
- Ashley E. Brady 1 , 5 ,
- Albert A. Davis 8 ,
- Zixiu Xiang 1 ,
- Michael Bubser 3 ,
- Mohammed Noor Tantawy 6 ,
- Alexander S. Kane 1 ,
- Thomas M. Bridges 1 ,
- J. Phillip Kennedy 2 ,
- Stefania R. Bradley 7 ,
- Todd E. Peterson 4 , 6 ,
- M. Sib Ansari 4 , 6 ,
- Ronald M. Baldwin 4 , 6 ,
- Robert M. Kessler 4 ,
- Ariel Y. Deutch 1 , 3 ,
- James J. Lah 8 ,
- Allan I. Levey 8 ,
- Craig W. Lindsley 1 , 2 , 5 , and
- P. Jeffrey Conn 1 , 5
- Departments of 1Pharmacology,
- 2Chemistry,
- 3Psychiatry, and
- 4Radiology and Radiological Sciences/PET Chemistry,
- 5Vanderbilt Program in Drug Discovery, and
- 6Vanderbilt University Institute of Imaging Science, Vanderbilt University Medical Center, Nashville, Tennessee 37232,
- 7ACADIA Pharmaceuticals, San Diego, California 92121, and
- 8Center for Neurodegenerative Disease and Department of Neurology, Emory University, Atlanta, Georgia 30322
- Correspondence should be addressed to Dr. P. Jeffrey Conn, Director, Vanderbilt Program in Drug Discovery, Department of Pharmacology, Vanderbilt University Medical Center, 2220 Pierce Avenue, 1215 Light Hall, Nashville, TN 37232-6600. jeff.conn{at}vanderbilt.edu
Author contributions
Disclosures
- Received April 27, 2008.
- Revision received July 20, 2008.
- Accepted July 30, 2008.
-
This work was supported by grants from the National Institute of Mental Health (P.J.C., C.K.J., A.E.B.), the National Institute of Neurological Disorders and Stroke (A.I.L.), and Alzheimer's Association Grant IIRG-07-57131 (C.W.L.), a predoctoral fellowship from the National Institute on Aging and the PhRMA Foundation (A.A.D.), the Dystonia Medical Research Foundation Grant (Z.X.), and Career Award at the Scientific Interface from the Burroughs Wellcome Fund (T.E.P.). Vanderbilt is a site in the National Institutes of Health-supported Molecular Libraries Screening Center Network. Parts of this work have been presented previously at the 45th Annual Meeting of the American College of Neuropsychopharmacology, Hollywood, Florida, December 3–7, 2006.
- Correspondence should be addressed to Dr. P. Jeffrey Conn, Director, Vanderbilt Program in Drug Discovery, Department of Pharmacology, Vanderbilt University Medical Center, 2220 Pierce Avenue, 1215 Light Hall, Nashville, TN 37232-6600. jeff.conn{at}vanderbilt.edu
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