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Brief Communications

Exercise-Induced Synaptogenesis in the Hippocampus Is Dependent on UCP2-Regulated Mitochondrial Adaptation

Marcelo O. Dietrich, Zane B. Andrews and Tamas L. Horvath
Journal of Neuroscience 15 October 2008, 28 (42) 10766-10771; https://doi.org/10.1523/JNEUROSCI.2744-08.2008
Marcelo O. Dietrich
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Zane B. Andrews
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Tamas L. Horvath
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Article Information

DOI 
https://doi.org/10.1523/JNEUROSCI.2744-08.2008
PubMed 
18923051
Published By 
Society for Neuroscience
History 
  • Received June 16, 2008
  • Revision received August 24, 2008
  • Accepted September 11, 2008
  • First published October 15, 2008.
  • Version of record published October 15, 2008.
Copyright & Usage 
Copyright © 2008 Society for Neuroscience 0270-6474/08/2810766-06$15.00/0

Author Information

  1. Marcelo O. Dietrich1,2,3,4,
  2. Zane B. Andrews1,2,3,5, and
  3. Tamas L. Horvath1,2,3
  1. 1Section of Comparative Medicine and
  2. Departments of 2Obstetrics, Gynecology, and Reproductive Sciences and
  3. 3Neurobiology, Yale University School of Medicine, New Haven, Connecticut 06520,
  4. 4Programa de Pós-graduação em Bioquímica de Bioquímica, Universidade Federal do Rio Grande do Sul, 90035-003 Porto Alegre, RS, Brazil, and
  5. 5Department of Physiology, Monash University, Clayton, Victoria 3183 Australia
  1. Correspondence should be addressed to Tamas L. Horvath, Section of Comparative Medicine, Yale University School of Medicine, 375 Congress Avenue, LSOG 117, New Haven, CT 06520. tamas.horvath{at}yale.edu
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Author contributions

Disclosures

    • Received June 16, 2008.
    • Revision received August 24, 2008.
    • Accepted September 11, 2008.
  • This work was supported by National Institutes of Health Grants DK 074386, DK 060711, DK 080000, and AG 022880 (T.L.H.). M.O.D. was supported by Conselho Nacional de Desenvolvimento Científico e Tecnológico, and Z.B.A. was the recipient of a New Zealand Foundation for Research Science and Technology Fellowship. We are indebted to Marya Shanabrough and Erzsebet Borok for their superb technical assistance and Dr. Brad Lowell for providing breeding pairs of UCP2 knock-out mice.

  • Correspondence should be addressed to Tamas L. Horvath, Section of Comparative Medicine, Yale University School of Medicine, 375 Congress Avenue, LSOG 117, New Haven, CT 06520. tamas.horvath{at}yale.edu

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The Journal of Neuroscience: 28 (42)
Journal of Neuroscience
Vol. 28, Issue 42
15 Oct 2008
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Exercise-Induced Synaptogenesis in the Hippocampus Is Dependent on UCP2-Regulated Mitochondrial Adaptation
Marcelo O. Dietrich, Zane B. Andrews, Tamas L. Horvath
Journal of Neuroscience 15 October 2008, 28 (42) 10766-10771; DOI: 10.1523/JNEUROSCI.2744-08.2008

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Exercise-Induced Synaptogenesis in the Hippocampus Is Dependent on UCP2-Regulated Mitochondrial Adaptation
Marcelo O. Dietrich, Zane B. Andrews, Tamas L. Horvath
Journal of Neuroscience 15 October 2008, 28 (42) 10766-10771; DOI: 10.1523/JNEUROSCI.2744-08.2008
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