Figure 6.
Modulation of tonic inhibition influences SPN firing properties. Recordings made in K-gluconate intracellular solution. A1–2, Reponses of an SPN to depolarizing current steps (+10, +20, +30 pA, left to right) under control conditions and during bath application of 100 μm bicuculline. A3, Graph showing mean action potential frequency against injected current step in the same SPN. B1, Responses of a different SPN to injecting currents (−80, −50, −30, −20, −10, +30 pA) under control conditions (left) and during bath application of 1 μm diazepam (diaz, right). B2, Plot of mean action potential frequency against injected current step in the same SPN.