Article Information
- Received August 15, 2008
- Accepted October 7, 2008
- First published November 26, 2008.
- Version of record published November 26, 2008.
Author Information
- Xi Chen1,
- Tie-Shan Tang1,
- Huiping Tu1,
- Omar Nelson1,
- Mark Pook3,
- Robert Hammer2,
- Nobuyuki Nukina4, and
- Ilya Bezprozvanny1
- Departments of 1Physiology and
- 2Biochemistry, University of Texas Southwestern Medical Center, Dallas, Texas 75390,
- 3School of Health Sciences and Social Care, Brunel University, Uxbridge, Middlesex UB8 3PH, United Kingdom, and
- 4Laboratory for Structural Neuropathology, RIKEN Brain Science Institute, Saitama 351-0198, Japan
- Correspondence should be addressed to Dr. Ilya Bezprozvanny at the above address. ilya.bezprozvanny{at}utsouthwestern.edu
Author contributions
Disclosures
- Received August 15, 2008.
- Accepted October 7, 2008.
-
This work was supported by The McKnight Neuroscience of Brain Disorders Award, Robert A. Welch Foundation, National Ataxia Foundation, Ataxia MJD Research Project, and National Institute of Neurological Disorders and Stroke (NINDS) Grants R01NS38082 and R01NS056224 (I.B.); the Division of Basic Science Training Grant and National Institutes of Health (NIH) Predoctoral Fellowship Award for Minority Students F31 AG031692 (O.N.); Ataxia UK and Ataxia MJD Research Project (M.P.); and Ministry of Education, Culture, Sports, Science, and Technology of Japan Grant-in-Aid 17025044 (N.N.). The monoclonal anti-InsP3R1 antibody L24/18 was developed and obtained from the University of California at Davis/NINDS/National Institute of Mental Health NeuroMab Facility supported by NIH Grant U24NS05060. I.B. is a holder of Carla Cocke Francis Professorship in Alzheimer's Research. We thank Xiangmei Kong, Tianhua Lei, and Huarui Liu for help with maintaining the SCA3 mouse colony; Janet Young and Leah Benson for administrative assistance; Noelle Williams for assistance with the measurements of dantrolene concentrations; Lisa Monteggia, Jenny Hsieh, Malu Tansey, Keith Tansey, and Don Cooper for help and advice with behavioral and stereological experiments; Henry Paulson for the gift of human-specific ATX3 polyclonal antibody; and Andrew Marks for the gift of rat RyanR1 expression plasmid.
- Correspondence should be addressed to Dr. Ilya Bezprozvanny at the above address. ilya.bezprozvanny{at}utsouthwestern.edu
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