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Articles, Neurobiology of Disease

Loss of LR11/SORLA Enhances Early Pathology in a Mouse Model of Amyloidosis: Evidence for a Proximal Role in Alzheimer's Disease

Sara E. Dodson, Olav M. Andersen, Vinit Karmali, Jason J. Fritz, Dongmei Cheng, Junmin Peng, Allan I. Levey, Thomas E. Willnow and James J. Lah
Journal of Neuroscience 26 November 2008, 28 (48) 12877-12886; DOI: https://doi.org/10.1523/JNEUROSCI.4582-08.2008
Sara E. Dodson
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Olav M. Andersen
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Vinit Karmali
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Jason J. Fritz
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Dongmei Cheng
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Junmin Peng
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Allan I. Levey
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Thomas E. Willnow
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James J. Lah
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Article Information

DOI 
https://doi.org/10.1523/JNEUROSCI.4582-08.2008
PubMed 
19036982
Published By 
Society for Neuroscience
History 
  • Received September 13, 2008
  • Accepted October 15, 2008
  • First published November 26, 2008.
  • Version of record published November 26, 2008.
Copyright & Usage 
Copyright © 2008 Society for Neuroscience 0270-6474/08/2812877-10$15.00/0

Author Information

  1. Sara E. Dodson1,
  2. Olav M. Andersen4,
  3. Vinit Karmali1,
  4. Jason J. Fritz1,2,
  5. Dongmei Cheng1,3,
  6. Junmin Peng1,3,
  7. Allan I. Levey1,2,
  8. Thomas E. Willnow5, and
  9. James J. Lah1,2
  1. 1Center for Neurodegenerative Disease,
  2. Departments of 2Neurology and
  3. 3Human Genetics, Emory University, Atlanta, Georgia 30322,
  4. 4The MIND Center, Department of Medical Biochemistry, Aarhus University, 8000 Aarhus, Denmark, and
  5. 5Max-Delbrueck-Center for Molecular Medicine, D-13125 Berlin, Germany
  1. Correspondence should be addressed to either of the following: James J. Lah, Center for Neurodegenerative Disease, 615 Michael Street, Suite 505 S, Atlanta, GA 30322, jlah{at}emory.edu; or Thomas E. Willnow, Max-Delbrueck-Center for Molecular Medicine, R. Roessle Strasse 10, D-13125 Berlin, Germany, E-mail: willnow{at}mdc-berlin.de
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Author contributions

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Disclosures

    • Received September 13, 2008.
    • Accepted October 15, 2008.
  • This work was supported by National Institutes of Health Grants AG05136 (J.J.L.) and F31 NS055881 (S.E.D.), and by the Deutsche Forschungsgemeinschaft (T.E.W.). We gratefully acknowledge Stephanie Carter for excellent technical assistance and Joanne Wuu for providing expert statistical advice.

  • Correspondence should be addressed to either of the following: James J. Lah, Center for Neurodegenerative Disease, 615 Michael Street, Suite 505 S, Atlanta, GA 30322, jlah{at}emory.edu; or Thomas E. Willnow, Max-Delbrueck-Center for Molecular Medicine, R. Roessle Strasse 10, D-13125 Berlin, Germany, E-mail: willnow{at}mdc-berlin.de

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Article usage: November 2008 to January 2021

AbstractFullPdf
Nov 200820253137
Dec 2008106140211
Total 2008308193348
Jan 2009287159
Feb 2009285252
Mar 2009483536
Apr 2009513020
May 2009112424
Jun 2009205240
Jul 2009204123
Aug 2009162520
Sep 2009132939
Oct 2009232319
Nov 2009513534
Dec 2009413030
Total 2009350447396
Jan 2010502620
Feb 2010121921
Mar 201093033
Apr 2010114118
May 2010213624
Jun 2010113820
Jul 2010101614
Aug 2010312418
Sep 2010252720
Oct 201022127
Nov 201072328
Dec 201071410
Total 2010216306233
Jan 201152415
Feb 201110125
Mar 2011151917
Apr 2011101316
May 201110816
Jun 2011101014
Jul 201118913
Aug 2011191025
Sep 2011111016
Oct 2011252116
Nov 2011191318
Dec 2011191315
Total 2011171162186
Jan 2012171419
Feb 2012221127
Mar 2012241717
Apr 2012161211
May 2012251512
Jun 2012231611
Jul 2012341514
Aug 201220510
Sep 2012271112
Oct 201222129
Nov 2012401610
Dec 201244810
Total 2012314152162
Jan 201319148
Feb 201333711
Mar 2013192111
Apr 2013191612
May 201316510
Jun 20131083
Jul 20131887
Aug 2013201110
Sep 2013584
Oct 201317118
Nov 201315117
Dec 201316145
Total 201320713496
Jan 201419109
Feb 201418718
Mar 2014212420
Apr 2014381521
May 2014241432
Jun 201423510
Jul 201415145
Aug 201415118
Sep 201415139
Oct 201417912
Nov 20142346
Dec 201434159
Total 2014262141159
Jan 201520147
Feb 20152543
Mar 201532239
Apr 20151567
May 20151040
Jun 20151885
Jul 20151067
Aug 20152058
Sep 201513115
Oct 201515115
Nov 20151313
Dec 201523163
Total 201521410962
Jan 201674711
Feb 2016491311
Mar 2016261413
Apr 20161979
May 20161771
Jun 20161685
Jul 20162012
Aug 2016964
Sep 20167101
Oct 2016796
Nov 20166148
Dec 20162245
Total 201625212076
Jan 20172196
Feb 20172235
Mar 201713311
Apr 20170157
May 20172416
Jun 2017186
Jul 20174258
Aug 20171179
Sep 2017088
Oct 201712011
Nov 201741557
Dec 2017375
Total 201721231139
Jan 201852113
Feb 201841517
Mar 201812413
Apr 20182145
May 20180203
Jun 20181111
Jul 20180112
Aug 20183176
Sep 20180256
Oct 20183259
Nov 20185294
Dec 20180144
Total 20182422683
Jan 2019181
Feb 20191176
Mar 20192259
Apr 20192195
May 20191113
Jun 20192145
Jul 20190156
Aug 201901910
Sep 20192418
Oct 20197507
Nov 201921119
Dec 201941411
Total 20192424490
Jan 20200167
Feb 20202144
Mar 20202811
Apr 20205113
May 20201102
Jun 20201131
Jul 20203115
Aug 202031713
Sep 20204317
Oct 202042715
Nov 202053313
Dec 20202249
Total 20203221590
Jan 20211136
Total 20211136
Total239626932126
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The Journal of Neuroscience: 28 (48)
Journal of Neuroscience
Vol. 28, Issue 48
26 Nov 2008
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Loss of LR11/SORLA Enhances Early Pathology in a Mouse Model of Amyloidosis: Evidence for a Proximal Role in Alzheimer's Disease
Sara E. Dodson, Olav M. Andersen, Vinit Karmali, Jason J. Fritz, Dongmei Cheng, Junmin Peng, Allan I. Levey, Thomas E. Willnow, James J. Lah
Journal of Neuroscience 26 November 2008, 28 (48) 12877-12886; DOI: 10.1523/JNEUROSCI.4582-08.2008

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Loss of LR11/SORLA Enhances Early Pathology in a Mouse Model of Amyloidosis: Evidence for a Proximal Role in Alzheimer's Disease
Sara E. Dodson, Olav M. Andersen, Vinit Karmali, Jason J. Fritz, Dongmei Cheng, Junmin Peng, Allan I. Levey, Thomas E. Willnow, James J. Lah
Journal of Neuroscience 26 November 2008, 28 (48) 12877-12886; DOI: 10.1523/JNEUROSCI.4582-08.2008
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