Figure 1.
NGR locus is associated with schizophrenia in a Caucasian case–control study. A, Linkage disequilibrium plot. The relative position of the five SNPs relative to the NGR locus are depicted. B, Association of specific single markers with the disease. The five markers selected were in Hardy–Weinberg equilibrium (p > 0.05). HWE, Hardy–Weinberg p value; MA, minor allele; control, allele frequency in the control samples; case, allele frequency in the schizophrenic samples. C, Association of the haplotype obtained by analyzing the five SNPs with the disease. For each haplotype, 0 represents the major allele and 1 represents the minor allele. The order of the SNPs in haplotypes does not follow the order of the chromosomal position; it follows this order: rs9606296, rs701421, rs701428, rs1567871, rs696880. Uncorrected p values and values corrected for multiple testing are listed.
