Article Information
- Received October 4, 2007
- Revision received December 7, 2007
- Accepted December 9, 2007
- First published January 30, 2008.
- Version of record published January 30, 2008.
Author Information
- Wang-Xia Wang1,*,
- Bernard W. Rajeev1,*,
- Arnold J. Stromberg2,
- Na Ren2,
- Guiliang Tang3,
- Qingwei Huang1,
- Isidore Rigoutsos5, and
- Peter T. Nelson1,4
- 1Sanders-Brown Center on Aging,
- 2Department of Statistics,
- 3Department of Plant Sciences, and
- 4Department of Pathology and Division of Neuropathology, University of Kentucky, Lexington, Kentucky 40536, and
- 5Bioinformatics and Pattern Discovery Group, IBM Thomas J. Watson Research Center, Yorktown Heights, New York 10598
- Correspondence should be addressed to Dr. Peter T. Nelson, 311 Sanders-Brown Center on Aging, University of Kentucky, 800 South Limestone, Lexington, KY 40536-0230. pnels2{at}email.uky.edu
Author contributions
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↵*W.-X.W. and B.W.R. contributed equally to this work.
Disclosures
- Received October 4, 2007.
- Revision received December 7, 2007.
- Accepted December 9, 2007.
-
This work was supported by National Institutes of Health (NIH) Grants K08 NS050110, P20 RR16481, and P30 AGO 28383. We thank members of the Sanders-Brown Center on Aging, and we are deeply grateful to all of the participants in our longitudinal aging study and to the patients in the University of Kentucky Alzheimer's Disease Center's research clinic. We also thank Ela Patel and Ann Tudor for technical support and Paul Thomason for help with preparation of this manuscript. We thank Dr. Kuey Chen for assistance with the Affymetrix Exon Arrays, and Dr. Don Baldwin and Robert Benjamin Isett for assistance in miRNA microarrays. We thank Dr. M. Paul Murphy for advice about BACE1 biochemistry. Finally, we are grateful to Dr. William Markesbery for his support in this project.
- Correspondence should be addressed to Dr. Peter T. Nelson, 311 Sanders-Brown Center on Aging, University of Kentucky, 800 South Limestone, Lexington, KY 40536-0230. pnels2{at}email.uky.edu
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